Evidence map›Paper›PMID 35752756›Full record

ArticleBMC geriatrics2022

Comorbidities and COVID-19 status influence the survival rate of geriatric patients in intensive care units: a prospective cohort study from the Indonesian Society of Anaesthesiology and Intensive Therapy.

Nancy Margarita Rehatta, Susilo Chandra, Djayanti Sari, Mayang Indah Lestari, Tjokorda Gde Agung Senapathi, Haizah Nurdin, Belindo Wirabuana, Bintang Pramodana, Adinda Putra Pradhana, Isngadi Isngadi and 7 more

Abstract read
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Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Nancy Margarita RehattaDepartment of Anaesthesiology and Reanimation, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Susilo ChandraDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Djayanti SariDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia.
Mayang Indah LestariDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine Universitas Sriwijaya, Jenderal Sudirman Street KM. 3.5, Palembang, South Sumatera, 30126, Indonesia. mayangindah@fk.unsri.ac.id.
Tjokorda Gde Agung SenapathiDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.
Haizah NurdinDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
Belindo WirabuanaDepartment of Anaesthesiology and Reanimation, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Bintang PramodanaDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Adinda Putra PradhanaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Udayana, Denpasar, Indonesia.
Isngadi IsngadiDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Brawijaya, Malang, Indonesia.
Novita AnggraeniDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Riau, Pekanbaru, Riau, Indonesia.
Kenanga Marwan SikumbangDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Lambung Mangkurat, Banjarmasin, Indonesia.
Radian Ahmad HalimiDepartment of Anaesthesiology and Intensive Care, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Zafrullah Khany JasaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Akhyar Hamonangan NasutionDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Mochamat MochamatDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia.
Purwoko PurwokoDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the more advanced science in the field of medicine and disease management, the population of geriatric intensive care patients is increasing. The COVID-19 pandemic has impacted healthcare management around the globe, especially on critically-ill elderly patients. We aim to analyse the relationship between underlying illnesses, including COVID-19, and the survival rate of elderly patients who are treated in the intensive care setting.

methodsWe conducted a prospective cohort study at 14 teaching hospitals for Anaesthesiology and Intensive Therapy Education in Indonesia. We selected all subjects with 60 years of age or older in the period between February to May 2021. Variables recorded included subject characteristics, comorbidities, and COVID-19 status. Subjects were followed for 30-day mortality as an outcome. We analysed the data using Kaplan-Meier survival analysis.

resultsWe recruited 982 elderly patients, and 728 subjects were in the final analysis (60.7% male; 68.0 ± 6.6 years old). The 30-day mortality was 38.6%. The top five comorbidities are hypertension (21.1%), diabetes (16.2%), moderate or severe renal disease (10.6%), congestive heart failure (9.2%), and cerebrovascular disease (9.1%). Subjects with Charlson's Comorbidity Index Score > 5 experienced 66% death. Subjects with COVID-19 who died were 57.4%. Subjects with comorbidities and COVID-19 had lower survival time than subjects without those conditions (p < 0.005). Based on linear correlation analysis, the more comorbidities the geriatric patients in the ICU had, the higher chance of mortality in 30 days (p < 0.005, R coefficient 0.22).

conclusionApproximately one in four elderly intensive care patients die, and the number is increasing with comorbidities and COVID-19 status.

Indexed as

AnesthesiologyCOVID-19AgedComorbidityFemaleHumansIndonesiaIntensive Care UnitsMalePandemicsProspective StudiesSurvival RateCharacteristicsGeriatricIntensive careOutcome

Identifiers

PMID35752756
PMCPMC9233386

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.