ArticleBMC geriatrics2022
Frailty trajectory among community-dwelling middle-aged and older adults in Korea: evidence from the Korean Longitudinal Study of Aging.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- Trajectories of Frailty and Depression and Their Associations with the Risk of Gastrointestinal and Liver Disease: Findings from China Health and Retirement Longitudinal Study and Validation of Survey of Health, Aging and Retirement in Europe.Healthcare (Basel, Switzerland) · 2026Article
- Association between physical activity and handgrip strength among older adults in the Korean longitudinal study of ageing.Scientific reports · 2025Article
- A survey on the trajectory of frailty in the middle-aged and elderly population in the Chengdu community: a retrospective observational study.BMC public health · 2025Observational
- Frailty trajectories and mortality risk in community-dwelling older adults: a 9-year follow-up study.European geriatric medicine · 2025Article
- Alcohol dependence trajectories and smoking cessation among Korean men who smoke: A secondary data analysis from the Korean longitudinal study of aging dataset.Tobacco induced diseases · 2025Article
- Development and validation of nomograms to predict frailty-worsening trajectories among Chinese older adults.Frontiers in public health · 2025Article
- Progression of frailty and cardiovascular outcomes among Medicare beneficiaries.Journal of the American Geriatrics Society · 2024Article
- Effect of leisure activity on frailty trajectories among Chinese older adults: a 16-year longitudinal study.BMC geriatrics · 2024Article
- Pre-frailty after blood or marrow transplantation and the risk of subsequent mortality.Leukemia · 2024Article
- Sex differences in the frailty phenotype and mortality in the I-Lan longitudinal aging study cohort.BMC geriatrics · 2024Article
- Progression of Frailty and Cardiovascular Outcomes Among Medicare Beneficiaries.medRxiv : the preprint server for health sciences · 2024Article
- Comparative Study of the Accuracy of At-Point Clinical Frailty Scale and Morse Fall Scale in Identifying High-Risk Fall Patients among Hospitalized Adults.Annals of geriatric medicine and research · 2023Article
- Effect of hearing loss on cognitive function in patients with mild cognitive impairment: A prospective, randomized, and controlled study.Frontiers in aging neuroscience · 2022Article
- Analyzing Frailty Trajectories and Predictive Factors in Older Chinese Adults: A Group-Based Trajectory Modeling.Public health nursing (Boston, Mass.)Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is no study on the frailty trajectory including both middle-aged and older people, and the understanding of the long-term frailty trajectory is insufficient. This study aimed to identify the frailty trajectory, subgroups of the frailty trajectory, and the predictors that differentiate these subgroups among community-dwelling middle-aged and older adults.
methodsThe participants were 9,775 individuals aged 45 years and older who participated in the Korean Longitudinal Study of Aging (2006-2018). Frailty was measured using a frailty instrument comprising three items: grip strength weakness, exhaustion, and social isolation. Latent growth curve modeling and latent class growth modeling were performed to identify the frailty trajectory and latent classes of the trajectory. Multinomial logistic regression was used to confirm the predictors that classified the latent classes.
resultsOver 12 years, the slope of the frailty trajectory among the participants showed a gradual increase. In addition, there was a difference in the latent class of frailty trajectories among middle-aged and older adults. The middle-aged participants were divided into two groups: maintaining robustness and changing from pre-frailty to robustness. The older adults were divided into three groups: maintaining robustness, maintaining pre-frailty, and changing from the frailty to pre-frailty group. Regular exercise, cognitive dysfunction, and social participation were significant predictors that differentiated each latent class in both middle-aged and older adults; additionally, current smoking and the number of chronic diseases were significant predictors in middle-aged people.
conclusionsVarious subgroups within the frailty trajectory existed among community-dwelling middle-aged and older adults. To reduce frailty, it is necessary to intervene with modifiable factors appropriate for each age group.
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