ArticleScientific reports2022
Multi-omics reveals mechanisms of resistance to potato root infection by Spongospora subterranea.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Multi-omics revolution to promote plant breeding efficiency.Frontiers in plant science · 2022Pooled it
- Metabolomics in Biotic Stress: Insights into Potato Resistance to Powdery Scab.Plants (Basel, Switzerland) · 2026Article
- Powdery Scab of Potato: An Evaluation of Current Molecular Resources.Environmental microbiology reports · 2026Review
- Dynamic transcriptomic responses reveal candidate defense genes againstFrontiers in plant science · 2026Article
- Omics Sciences: Driving the Conservation and Characterization of Plant Genetic Resources.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Plant-pathogen interactions: making the case for multi-omics analysis of complex pathosystems.Stress biology · 2025Review
- Investigating the Potential Involvement of Glutathione S-Transferases in Defence Against Powdery Scab in Potato.Journal of fungi (Basel, Switzerland) · 2025Article
- Unveiling molecular mechanisms and candidate genes for goss's bacterial wilt and leaf blight resistance in corn through RNA-Seq analysis.BMC genomics · 2025Article
- PotatoBSLnc: a curated repository of potato long noncoding RNAs in response to biotic stress.Database : the journal of biological databases and curation · 2025Article
- Transcriptome responses toHeliyon · 2025Article
- Recent advances in the improvement of genetic resistance against disease in vegetable crops.Plant physiology · 2024Review
- Transcriptomics is essential but not sufficient to unravel complex plant-pathogen interactions.Plant cell reports · 2024Article
- Enzymatic Investigation ofProteomes · 2023Article
- Comparative Proteomic Analysis of Potato Roots from Resistant and Susceptible Cultivars toMolecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The pathogen Spongospora subterranea infects potato roots and developing tubers resulting in tuber yield and quality losses. Currently, there are no fully effective treatments for disease control. Host resistance is an important tool in disease management and understanding the molecular mechanisms of defence responses in roots of potato plants is required for the breeding of novel resistant cultivars. Here, we integrated transcriptomic and proteomic datasets to uncover these mechanisms underlying S. subterranea resistance in potato roots. This multi-omics approach identified upregulation of glutathione metabolism at the levels of RNA and protein in the resistant cultivar but not in the susceptible cultivar. Upregulation of the lignin metabolic process, which is an important component of plant defence, was also specific to the resistant cultivar at the transcriptome level. In addition, the inositol phosphate pathway was upregulated in the susceptible cultivar but downregulated in the resistant cultivar in response to S. subterranea infection. We provide large-scale multi-omics data of Spongospora-potato interaction and suggest an important role of glutathione metabolism in disease resistance.
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