Evidence map›Paper›PMID 35751871›Full record

ArticleAge and ageing2022

Trajectories of physical functioning among US adults with cognitive impairment.

Emma Zang, Yu Shi, Xueqing Wang, Bei Wu, Terri R Fried

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04922320 (Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04922320 nacompletednot on this map

Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions

TypeinterventionalSponsorVA Office of Research and DevelopmentRan2022 to 2025Enrolled420ConditionsMultiple Chronic Conditions, Decision Making, SharedArmsPatient Priorities Care, Usual Care
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Dementia Severity Associated With Unmet Caregiving Needs During Skilled Home Health Care.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
    Article
  3. Article
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  8. Association of Family Support With Lower Modifiable Risk Factors for Dementia Among Cognitively Impaired Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Emma ZangDepartment of Sociology, Yale University, New Haven, CT 06520, USA.ORCID 0000-0002-5700-3179
Yu ShiDepartment of Biostatistics, Yale University, New Haven, CT 06520, USA.
Xueqing WangOffice of Population Research, Princeton University, Princeton, NJ 08540, USA.ORCID 0000-0002-1749-0769
Bei WuRory Meyers College of Nursing, New York University, New York, NY 10010, USA.
Terri R FriedVeterans Affairs Connecticut Healthcare System, West Haven, CT 06516, USA.
Yale University · USNew York University · USPrinceton University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Denise Esserman · 2002 to 2026
$37.9M
Linked Lives, Linked Health: Health Trajectories of Persons with Cognitive Impairment and Their Caregivers' HealthR21AG074238 · NIA · YALE UNIVERSITY · PI ZANG, EMMA · 2021 to 2022
$473k
NCATS NIH HHS UL1 TR001863NIA NIH HHS P30 AG021342NIA NIH HHS R21AG074238-01
6 · The paper itself

Abstract

backgroundphysical functioning impairment is common among persons with cognitive impairment, but little is known about physical functioning trajectories across the US population or how trajectories may differ among persons with dementia and mild cognitive impairment (MCI).

objectiveto examine trajectories of physical functioning among persons with MCI and dementia in the USA.

designwe used data from the National Health and Aging Trends study (NHATS) 2011-18. Physical functioning was assessed using the NHATS Expanded Short Physical Performance Battery.

participantsthe 661 individuals with MCI and 980 individuals with dementia were included in this study.

methodswe applied group-based trajectory models to identify latent groups and estimate their trajectories. Multinomial logistic regressions were applied to examine relationships between sociodemographic and health characteristics and trajectory group memberships.

resultsboth MCI- and dementia-specific trajectories differed at baseline levels and declined at varying rates across groups. Approximately, 78.43% of persons with MCI were in trajectories with a moderate rate of decline, with only 9.75% in a trajectory with good physical function and 11.82% with poor physical function without as much change over time. Among persons with dementia, approximately 81.4% experienced moderate or fast declines, and 18.52% with virtually no functional ability remained at this same low level. Worse physical functioning trajectories were found among persons who were females, Blacks, with at least four comorbidities, and among persons who had a low socioeconomic status.

conclusionspersons with both dementia and MCI experienced steady declines in physical functioning. Socioeconomically disadvantaged groups have worse physical functioning trajectories.

Indexed as

Cognitive DysfunctionDementiaActivities of Daily LivingAgingFemaleHumansMaledementiagroup-based trajectory modelsmild cognitive impairmentolder peoplephysical functioning

Identifiers

PMID35751871
PMCPMC9233517
OpenAlexW4283455776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.