Evidence map›Paper›PMID 35751746›Full record

Observational studyEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

Impact of medical and pharmaceutical interventions on anti-infective prescriptions: an observational study.

Emma Pinet, P Sabatier, M P Fernandez-Gerlinger, A S Jannot, J L Mainardi, B Sabatier, T Caruba

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma PinetPharmacy Department, Georges Pompidou European Hospital, AP-HP, 75015, Paris, France. emma.pinet@wanadoo.fr.ORCID http://orcid.org/0000-0002-2293-1696
P SabatierMedical Information Department, Georges Pompidou European Hospital, AP-HP, 75015, Paris, France.
M P Fernandez-GerlingerInfectious Disease Department, Georges Pompidou European Hospital, AP-HP, 75015, Paris, France.
A S JannotMedical Information Department, Georges Pompidou European Hospital, AP-HP, 75015, Paris, France.
J L MainardiUniversity Paris, INSERM U1138, 75006, Paris, France.
B SabatierPharmacy Department, Georges Pompidou European Hospital, AP-HP, 75015, Paris, France.
T CarubaPharmacy Department, Georges Pompidou European Hospital, AP-HP, 75015, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Appropriate prescribing of anti-infectives is a public health challenge. In our hospital, clinical microbiologists (clinical microbiology mobile unit, UMMc) and clinical pharmacists (clinical pharmacy, PHAc) carry out interventions on anti-infective prescriptions to improve practices. Our main objective was to evaluate the acceptance of UMMc and PHAc interventions on anti-infective prescriptions by quantifying the rate of prescription change 24 h after intervention. The secondary objective was to characterize the type of intervention and associate the rate of change for each. All prescriptions are computerized, and interventions traced via DxCare® software, which feeds a local data warehouse (HEGP-CDW). This descriptive, retrospective, single-center, uncontrolled study was conducted from January 2015 to December 2018. The data were extracted over this period from the data warehouse and analyzed using R software. UMMc interventions were accepted 72.2% of the time and PHA interventions 87.3%. The types of interventions found were mostly dose adjustments (61.1% for the UMMc and 54.2% for the PHAc) and proposals to change or stop a drug. Interventions have an impact on anti-infective prescriptions and are generally followed by clinicians. For the category "discontinuation of a molecule", almost half of the advice from the UMMc was refused. The collaboration between the UMMc and PHAc should be reinforced to improve acceptance.

Indexed as

Anti-Infective AgentsPharmacyDrug PrescriptionsHumansPharmaceutical PreparationsPrescriptionsRetrospective StudiesAnti-Infective AgentsPharmaceutical PreparationsAnti-infective useAntimicrobial stewardshipAppropriate prescribingInfectious disease teamPharmaceutical interventions

Identifiers

PMID35751746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.