Evidence map›Paper›PMID 35751731›Full record

ReviewCurrent atherosclerosis reports2022

A Narrative Review of the Association Between Depression and Heart Disease Among Women: Prevalence, Mechanisms of Action, and Treatment.

Danielle Rome, Alyssa Sales, Rebecca Leeds, John Usseglio, Talea Cornelius, Catherine Monk, Kim G Smolderen, Nathalie Moise

Abstract readReview
In one paragraph

Review in Current atherosclerosis reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Danielle RomeDepartment of Medicine, Columbia University Irving Medical Center/New York Presbyterian, New York, NY, USA.
Alyssa SalesColumbia University, New York, NY, USA.
Rebecca LeedsCenter for Family and Community Medicine, Columbia University Irving Medical Center/New York Presbyterian, New York, NY, USA.
John UsseglioCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Talea CorneliusCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Catherine MonkDepartments of OB/GYN and Psychiatry, School of Physicians and Surgeons, Columbia University Vagelos, New York, NY, USA.
Kim G SmolderenDepartments of Internal Medicine and Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Nathalie MoiseCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA. nm2562@cumc.columbia.edu.ORCID 0000-0002-5660-5573

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Institutional Career Development CoreKL2TR001874 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GENKINGER, JEANINE M., SHIMBO, DAICHI · 2016 to 2025
$13.6M
Depression Screening RCT in ACS patients: Quality of Life and Cost OutcomesR01HL114924 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KRONISH, IAN MATTHEW · 2013 to 2017
$4.2M
An Information tecHnology approach to implEmenting depression treAtment in caRdiac patienTs: [iHeart Trial]R01HL141609 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MOISE, NATHALIE · 2018 to 2022
$4.0M
NCATS NIH HHS KL2 TR001874NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL114924NHLBI NIH HHS R01 HL141609
6 · The paper itself

Abstract

purpose of reviewSex and gender differences exist with regard to the association between depression and cardiovascular disease (CVD). This narrative review describes the prevalence, mechanisms of action, and management of depression and CVD among women, with a particular focus on coronary heart disease (CHD). RECENT

findingsWomen versus men with incident and established CHD have a greater prevalence of depression. Comorbid depression and CHD in women may be associated with greater mortality, and treatment inertia. Proposed mechanisms unique to the association among women of depression and CHD include psychosocial, cardiometabolic, behavioral, inflammatory, hormonal, and autonomic factors. The literature supports a stronger association between CHD and the prevalence of depression in women compared to men. It remains unclear whether depression treatment influences cardiovascular outcomes, or if treatment effects differ by sex and/or gender. Further research is needed to establish underlying mechanisms as diagnostic and therapeutic targets.

Indexed as

Cardiovascular DiseasesCoronary DiseaseDepressionFemaleHumansMalePrevalenceRisk FactorsSex FactorsCardiovascular diseaseCoronary heart diseaseDepressionGender differencesSex differencesWomen

Identifiers

PMID35751731
PMCPMC9398966

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.