Evidence map›Paper›PMID 35751643›Full record

ArticleJournal of cutaneous pathology2022

Cutaneous melanocytic tumor with CRTC1::TRIM11 fusion and prominent epidermal involvement: A case report.

Blake E Vest, Christina L Harview, Vincent Liu, Brian L Swick, Kristen G Berrebi, Shantel Olivares, Mary S Stone, Michael R Sargen, Pedram Gerami

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of cutaneous pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. [Cutaneous clear cell sarcoma].Pathologie (Heidelberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Blake E VestDepartment of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0002-4198-2296
Christina L HarviewDepartment of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Vincent LiuDepartment of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0003-1987-9521
Brian L SwickDepartment of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Kristen G BerrebiDepartment of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Shantel OlivaresDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Mary S StoneDepartment of Dermatology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Michael R SargenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.
Pedram GeramiDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
University of Iowa Hospitals and Clinics · USNorthwestern University · USNational Institutes of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous melanocytic tumor with CRTC1::TRIM11 fusion (CMCT) is a recently described entity with only 13 cases reported in the literature. Histopathologically, the neoplasm consists of atypical epithelioid to spindled cells that form a well-circumscribed nodule usually confined to the dermis and subcutis with cytological features including large vesicular nuclei with prominent nucleoli and abundant eosinophilic cytoplasm. Immunohistochemistry shows variable expressivity of melanocytic markers. Currently, there are limited data regarding long-term outcomes of this newly described entity. Most cases have done well, but there is one case reported with an adverse event. Hence, further studies are needed to accurately classify this tumor. Definitive diagnosis is made by laboratory evidence of CMCT. Herein, we report the first case of CMCT with epidermal involvement in the youngest patient known to be affected to date.

Indexed as

Skin NeoplasmsBiomarkers, TumorCME-CarbodiimideGene FusionHumansMelanocytesTranscription FactorsTripartite Motif ProteinsUbiquitin-Protein Ligases1-cyclohexyl-3-(2-(4-morpholinyl)ethyl)carbodiimideBiomarkers, TumorCME-CarbodiimideCRTC1 protein, humanTranscription FactorsTRIM11 protein, humanTripartite Motif ProteinsUbiquitin-Protein Ligasescase reportclear cell sarcomaCRTC1melanocytomaTRIM11

Identifiers

PMID35751643
PMCPMC10086857
OpenAlexW4283461637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.