ArticleTransfusion medicine (Oxford, England)2022
Detection frequencies and viral load distribution of parvovirus B19 DNA in blood and plasma donations in England.
Article in Transfusion medicine (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 16 citations in OpenAlex.
- A decision-making process to guide the potential application of a hepatitis A virus and parvovirus B19 nucleic acid test for qualifying plasma for fractionation.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026Article
- Multiple Mononeuropathy Secondary to Parvovirus B19 Infection: A Case Series.European journal of neurology · 2026Observational
- Molecular and serologic analysis of linked blood donor and recipient samples to rule out transfusion-transmitted parvovirus B19 infection.Frontiers in public health · 2026Article
- Seroepidemiology (2018-2024) and epidemic spread of an emerging human parvovirus B19 genotype 1 (subtype 1a2) variant in Hungary, 2023/2024.Archives of virology · 2025Article
- Incidence and estimated risk of residual transmission of hepatitis a virus and parvovirus B19 by blood transfusion in the state of Rio De Janeiro - Brazil: a retrospective study.Virology journal · 2025Article
- Review
- New atypical epidemiological profile of parvovirus B19 revealed by molecular screening of blood donations, France, winter 2023/24.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024Article
- An Outbreak of Parvovirus B19 in Israel.Viruses · 2023Article
- Detection frequencies and viral load distribution of parvovirus B19 DNA in blood and plasma donations in England.Transfusion medicine (Oxford, England) · 2022Article
- Surveillance of blood donors detects an exceptional Parvovirus B19 outbreak in Switzerland in 2023/2024.Blood transfusion = Trasfusione del sangueArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesInfections with human parvovirus B19 (B19V) are transmissible by blood components and plasma-derived medicines. The European Pharmacopoeia regulates maximum levels of virus allowed in manufacturers' plasma pools. To evaluate contamination risk prior to re-introduction of UK-sourced plasma for manufacturing, we investigated viraemia frequencies of B19V in plasma samples collected from blood donors before and during COVID-enforced lockdown. MATERIALS AND
methodsQuantitative PCR for B19V DNA was used to screen pools of 96 anonymised plasma samples collected in England from 2017 (n = 29 505), 2020 (n = 3360) and 2021 (n = 43 200). Selected positive pools were resolved into individual samples. Data on donor notifications and related lookback investigations were collected from European countries by on-line survey in 2020.
resultsScreening of 76 065 donations identified 80 B19V-positive pools. While most positive samples had low viral loads (<10
conclusionInformation on seroprevalence, incidence and viral loads of B19V viraemia is contributory the evaluation of alternative operational screening strategies for plasma testing.
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