Evidence map›Paper›PMID 35751519›Full record

ArticleDiagnostic cytopathology2022

Pronounced squamous cell contamination in biliary tract cytology: A diagnostic pitfall.

Nicole K Tomm, Laura W Lamps, Christopher Ko, Richard S Kwon, Richard Cantley, Liron Pantanowitz

Open access · hybridAbstract read
In one paragraph

Article in Diagnostic cytopathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Nicole K TommDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-2948-5510
Laura W LampsDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
Christopher KoDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Richard S KwonDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan, USA.
Richard CantleyDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-6564-3889
Liron PantanowitzDepartment of Pathology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0001-8182-5503
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Squamous cells are rarely found in biliary tract cytology specimens, and when present are typically scant in quantity. Over an 8-year time period, two cases at our institution reporting abundant squamous cells were identified. Both patients underwent endoscopic retrograde cholangiopancreatography with bile duct brushings and removal of a migrated biliary stent. The migrated stents were retrieved using rat toothed forceps and required removal of the endoscope through the esophagus with the stent exposed to esophageal and oral mucosa outside of the endoscope. Cytologic examination of the accompanying biliary stent material accordingly revealed abundant benign squamous cells. However, bile duct brushings showed benign ductal epithelial cells without squamous cells. Prior and subsequent cytology and bile duct surgical pathology specimens did not show squamous metaplasia. Migrated biliary stents that require endoscopic withdrawal increase the risk of contaminating samples with squamous cells. Recognition of this unique scenario is important, as the differential diagnosis includes squamous metaplasia and squamous neoplasia.

Indexed as

Carcinoma, Squamous CellCholangiopancreatography, Endoscopic RetrogradeBile DuctsEpithelial CellsHumansMetaplasiabile ductcontaminationcytologyendoscopymetaplasiasquamous cells

Identifiers

PMID35751519
PMCPMC9796303
OpenAlexW4283521007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.