Evidence map›Paper›PMID 35751446›Full record

ArticleActa ophthalmologica2023

Cost reduction in screening for retinopathy of prematurity in the Netherlands by comparing different screening strategies.

Kasia Trzcionkowska, Nicoline E Schalij-Delfos, Elske M E van den Akker-van Marle

Abstract read
In one paragraph

Article in Acta ophthalmologica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kasia TrzcionkowskaDepartment of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-0666-6746
Nicoline E Schalij-DelfosDepartment of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands.
Elske M E van den Akker-van MarleDepartment of Biomedical Data Sciences, Unit Medical Decision Making, Leiden University Medical Center, Leiden, The Netherlands.

Funding

ODAS Stichting 2016-02 NEDROP2
6 · The paper itself

Abstract

purposeEvaluate possibilities to reduce the number of infants screened for retinopathy of prematurity (ROP) and investigate costs and number of infants detected of current and alternative screening strategies in the Netherlands.

methodsProspective population-based study including clinical data from all infants born in 2017 and referred for ROP screening (NEDROP-2 study). Cost and effects of screening strategies were evaluated that differed on the criteria gestational age (GA), birth weight (BW) and presence of one or more specific risk factor(s) (RF): mechanical ventilation, sepsis, necrotizing enterocolitis, postnatal corticoids and/or hypotension treated with inotropic agents. RF obtained from the Dutch perinatal registry (Perined).

resultsOf the possible efficient strategies, the annual costs varied from €137 966 (inclusion of BW < 700, 63 infants eligible for screening, detection of 17/39 treated ROP) to €492 689 (GA < 30 weeks and BW < 1250 grams, together with infants with GA 30-32 and BW 1250-1500 grams with presence of one more RF, 744 infants eligible for screening, all treated infants detected). Total annual costs of the current Dutch guideline that detects all infants that need treatment for ROP amount to €552 143).

conclusionThe current Dutch ROP guideline can be improved by implementing new screening inclusion criteria. The most effective strategy detecting all severe and treated infants, reduces the number of screened infants by 24% compared to the current guideline and the overall annual costs by €59454.

Indexed as

Infant, Very Low Birth WeightRetinopathy of PrematurityBirth WeightChildGestational AgeHumansInfantInfant, NewbornNeonatal ScreeningNetherlandsProspective StudiesRetrospective StudiesRisk Factorscost-effectivenessguidelineimproved visionretinopathy of prematurityscreening

Identifiers

PMID35751446
PMCPMC10083946

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.