Evidence map›Paper›PMID 35750993›Full record

ArticleAAPS PharmSciTech2022

Luliconazole Nail Lacquer for the Treatment of Onychomycosis: Formulation, Characterization and In Vitro and Ex Vivo Evaluation.

Deepa Dehari, Abhishesh Kumar Mehata, Vishnu Priya, Dharmnath Parbat, Deepak Kumar, Anand Kumar Srivastava, Sanjay Singh, Ashish Kumar Agrawal

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Article in AAPS PharmSciTech, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Deepa DehariDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India.
Abhishesh Kumar MehataDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India.
Vishnu PriyaDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India.
Dharmnath ParbatDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India.
Deepak KumarDepartment of Microbiology, Institute of Medical Sciences (BHU), Varanasi, 221005, India.
Anand Kumar SrivastavaDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India. aksrivastava.phe@itbhu.ac.in.
Sanjay SinghDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India.
Ashish Kumar AgrawalDepartment of Pharmaceutical Engineering and Technology, Indian Institute of Technology (BHU), Varanasi, 221005, India. ashish.phe@iitbhu.ac.in.ORCID http://orcid.org/0000-0002-7302-3647
Indian Institute of Technology BHU · INBabasaheb Bhimrao Ambedkar University · INInstitute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Onychomycosis is the most common fungal infection of the nail affecting the skin under the fingertips and the toes. Currently, available therapy for onychomycosis includes oral and topical therapies, either alone or in combination. Oral antifungal medication has been associated with poor drug bioavailability and potential gastrointestinal and systemic side effects. The objective of this study was to prepare and evaluate the luliconazole nail lacquer (LCZ-NL) for the effective treatment of onychomycosis. In the current work, LCZ-NL was formulated in combination with penetration enhancers to overcome poor penetration. A 3

Indexed as

OnychomycosisAdministration, TopicalAntifungal AgentsHumansImidazolesLacquerNailsSolventsAntifungal AgentsImidazolesluliconazoleSolventsAntifungalLuliconazoleNail lacquersOnychomycosisTranungual

Identifiers

PMID35750993
OpenAlexW4283462139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.