Evidence map›Paper›PMID 35750970›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2022

Accidental administration of tranexamic acid into the epidural space: a case report.

Christopher L Pysyk, Lucie Filteau

Open access · bronzeAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Special announcement: Guidelines to the Practice of Anesthesia-Revised Edition 2024.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Article
  3. Preventing neuraxial administration of tranexamic acid.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Article
  4. In reply: Accidental infusion of tranexamic acid via a thoracic epidural catheter.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Article
  5. Article
  6. Accidental infusion of tranexamic acid via a thoracic epidural catheter.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Christopher L PysykThe Ottawa Hospital, General Campus, Ottawa, ON, Canada. cpysyk@toh.ca.
Lucie FilteauThe Ottawa Hospital, General Campus, Ottawa, ON, Canada.
Ottawa Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTranexamic acid administration into the epidural space has not been previously reported. We describe our experience managing and investigating a drug error involving incorrect route of tranexamic acid administration through an epidural catheter. CLINICAL FEATURES: A syringe containing tranexamic acid, intended for intravenous bolus and infusion intraoperatively using microbore tubing, was inadvertently attached to an epidural catheter via the Luer-type connector on the microbore tubing and epidural adapter.

conclusionsSaline lavage of the epidural space may be considered if tranexamic acid has been administered into the epidural space. Early multidisciplinary team involvement combined with repeated postevent neurologic monitoring is recommended to guide therapy. Adoption of neuraxial route-specific connectors, when available, may be warranted to reduce Luer-type misconnections.

Indexed as

Anesthesia, EpiduralTranexamic AcidEpidural SpaceHumansInjections, IntravenousMedication ErrorsTranexamic Acidepiduralmedication errortranexamic acidwrong route error

Identifiers

PMID35750970
OpenAlexW4283465376

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.