Evidence map›Paper›PMID 35750916›Full record

ArticleClinical neuroradiology2023

Meniscus Sign in Patients with Anterior Circulation Large Vessel Occlusion Stroke does not Predict Outcome.

André Miranda, Ramy Abdelnaby, André Araújo, Marta Rodrigues, Valeria Battistella, José Mário Roriz, Carmélia Rodrigues, Martin Wiesmann, Jörg B Schulz, Omid Nikoubashman and 3 more

Open access · hybridFull text read
In one paragraph

Article in Clinical neuroradiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

André MirandaInterventional Neuroradiology Unit, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
Ramy AbdelnabyDepartment of Neurology, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
André AraújoInterventional Neuroradiology Unit, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
Marta RodriguesInterventional Neuroradiology Unit, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
Valeria BattistellaStroke Unit, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
José Mário RorizStroke Unit, Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal.
Carmélia RodriguesStroke Unit, Unidade Local de Saúde do Alto Minho, Viana do Castelo, Portugal.
Martin WiesmannDepartment of Diagnostic and Interventional Neuroradiology, University Hospital, RWTH Aachen University, Aachen, Germany.
Jörg B SchulzDepartment of Neurology, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
Omid NikoubashmanDepartment of Diagnostic and Interventional Neuroradiology, University Hospital, RWTH Aachen University, Aachen, Germany.
Arno ReichDepartment of Neurology, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany.
Manuel RibeiroInterventional Neuroradiology Unit, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
João PinhoDepartment of Neurology, University Hospital, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany. jferreiradep@ukaachen.de.ORCID http://orcid.org/0000-0002-3977-7146
Centro Hospitalar de Vila Nova de Gaia · PTRWTH Aachen University · DEAdministração Regional de Saúde de Lisboa e Vale do Tejo · PTForschungszentrum Jülich · DEUnidade Local de Saúde de Entre Douro e Vouga · PTUniversitätsklinikum Aachen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe angiographic appearance of the occlusion site was suggested to influence outcomes of stroke patients with large vessel occlusion (LVO) who undergo endovascular treatment (EVT). We aimed to study the impact of the meniscus sign (MS) on outcomes of stroke patients with anterior circulation LVO.

methodsBased on two prospective registries of acute ischemic stroke, we selected patients with carotid‑T, M1 or M2 occlusion who underwent EVT. Clinical characteristics and outcomes were collected from the registries or from individual records. Two independent observers blinded to outcomes assessed the presence of MS in digital subtraction angiography before thrombectomy. Angiographic and clinical outcomes of patients with and without MS were compared.

resultsWe included 903 patients, with median age of 78 years, 59.8% were male, median baseline NIHSS was 14 and 39.5% received intravenous thrombolysis. Patients with MS (n = 170, 18.8%) were more frequently female, presented with higher NIHSS scores and more frequently underwent intravenous thrombolysis. Presence of MS was significantly associated with cardioembolic etiology. Successful reperfusion, number of passes, first pass effect, procedural time, symptomatic intracerebral hemorrhage, in-hospital mortality and favorable 3‑month functional outcome were similar in the groups of patients with and without MS. In the multivariable analyses, MS was not associated with successful reperfusion (odds ratio, OR = 1.08, 95% confidence interval, CI = 0.76-1.55), first pass effect (OR = 0.96, 95%CI = 0.48-1.92) or favorable 3‑month outcome (OR = 1.40, 95%CI = 0.88-2.24).

conclusionThe presence of MS in acute ischemic stroke patients with anterior circulation large vessel occlusion who undergo EVT does not appear to influence angiographic or clinical outcomes.

Indexed as

Brain IschemiaEndovascular ProceduresIschemic StrokeStrokeAgedFemaleHumansMaleProspective StudiesThrombectomyThrombolytic TherapyTreatment OutcomeDigital subtraction angiographyEndovascularIschemic strokePrognosisThrombectomy

Identifiers

PMID35750916
PMCPMC10014662
OpenAlexW4283391646

What OpenQuestion holds

Textfull text, public
LicenceCC BY
measurements read32
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.