ArticleScientific reports2022
Association between dietary acid load and metabolic health status in overweight and obese adolescents.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Metabolic syndrome in relation to dietary acid load: a dose-response meta-analysis of observational studies.Frontiers in nutrition · 2023Pooled it
- Association of Dietary Acid Load with Metabolic Syndrome-Related Parameters Following Eating Habit Modification in Korean Adults.Nutrients · 2026Article
- Association of dietary acid load with diabetes and glucose metabolism index in Chinese adults: a cross-sectional study.Food & nutrition research · 2026Article
- Association Between Dietary Acid Load and Excess Weight in Adults: A Cross-Sectional Study.Nutrients · 2025Article
- Association of dietary acid load with abdominal adiposity based on traditional and novel anthropometric indices.Journal of health, population, and nutrition · 2025Article
- The Effect of Dietary Acid Load on Cardiometabolic Risk, Psychological Resilience and Sleep Quality in Adolescents with ObesityJournal of clinical research in pediatric endocrinology · 2025Article
- Article
- Association of Genetic, Environmental, and Nutritional Factors With Metabolic Phenotypes of Obesity: A Scoping Review.Journal of obesity · 2025Article
- Effects of higher dietary acid load: a narrative review with special emphasis in children.Pediatric nephrology (Berlin, Germany) · 2025Review
- Dietary acid load and risk of diminished ovarian reserve: a case-control study.Reproductive biology and endocrinology : RB&E · 2024Article
- Higher dietary acid load is associated with an increased risk of metabolic syndrome.Scientific reports · 2023Article
- Higher Dietary Acid Load Might Be a Potent Derivative Factor for Multiple Sclerosis: The Results from a Case-Control Study.Nutrients · 2023Article
- Dietary acid load, alternative healthy eating index score, and bacterial vaginosis: is there any association? A case-control study.BMC infectious diseases · 2022Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between dietary acid load (DAL) and metabolic health status in adolescents has not been studied yet. We aimed to examine the association between DAL and metabolic health status in Iranian overweight/obese adolescents. This cross-sectional study included 203 overweight/obese adolescents selected by a multistage cluster random sampling method. Dietary intakes were assessed using a validated 147-item food frequency questionnaire (FFQ). Anthropometric indices and blood pressure values were measured. Fasting blood samples were obtained to determine glucose, insulin, and lipid profiles. Based on two methods (International Diabetes Federation (IDF) criteria and combination of IDF with Homeostasis Model Assessment Insulin Resistance (HOMA-IR)), participants were classified into metabolically healthy obese (MHO) or unhealthy obese (MUO). Adolescents in the highest tertile of potential renal acid load (PRAL) and net endogenous acid production (NEAP), compared with those in the lowest tertile, had 172% (95% CI 1.32-5.59) and 161% (95% CI 1.26-5.41) higher odds of MUO status, based on IDF criteria. This association was significant after adjustment for age, sex, and energy intake (PRAL: OR 2.42; 95% CI CI 1.13-5.15; NEAP: OR 2.52; 95% CI 1.17-5.41); but it disappeared after adjustment for other confounders. Based on IDF/HOMA-IR definition, there was a significant positive association between PRAL and being MUO only in the crude model (OR 2.37; 95% CI 1.13-4.96). The stratified analysis revealed that these associations for NEAP scores were stronger among overweight subjects than obese individuals, based on both metabolic status definitions. However, after adjustment for all potential confounders these relations were insignificant. Having higher DAL might be associated with higher odds of MUO phenotype in Iranian overweight/obese adolescents. More prospective studies are warranted to confirm this finding.
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