ArticleVaccine2022
Corowa-kun: A messenger app chatbot delivers COVID-19 vaccine information, Japan 2021.
Article in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Vaccine Chatbot on HPV Vaccine Awareness and Vaccination for Middle School Girls in China: a Randomized Controlled Trial and Implementation Science Study
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy: a Randomized Controlled Trial and Implementation Science Study
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Media Exposure and Its Association With Vaccine Attitudes, Intentions, and Hesitancy: Systematic Review.Journal of medical Internet research · 2026Pooled it
- Conversational AI and Vaccine Communication: Systematic Review of the Evidence.Journal of medical Internet research · 2023Pooled it
- Impact of Mobile Apps in Conjunction With Percutaneous Endoscopic Gastrostomy on Patients' Complications, Quality of Life, and Health-Related Self-Care Behaviors: Randomized Clinical Trial.JMIR mHealth and uHealth · 2023Trial
- Effect of a mobile app chatbot and an interactive small-group webinar on COVID-19 vaccine intention and confidence in Japan: a randomised controlled trial.BMJ global health · 2023Trial
- Understanding COVID-19 Vaccine Hesitancy among the General Population in Japan from Public Health Ethical Perspectives: Findings from a Narrative Review.Asian bioethics review · 2025Article
- Health, beliefs, and faith: HPV vaccine uptake intent among Catholic, Evangelical, and mainline protestant parents.Human vaccines & immunotherapeutics · 2024Article
- Mobile Apps for Vaccination Services: Content Analysis and Quality Assessment.Online journal of public health informatics · 2024Article
- Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.Journal of medical Internet research · 2024Review
- Advanced Mobile Communication Techniques in the Fight against the COVID-19 Pandemic Era and Beyond: An Overview of 5G/B5G/6G.Sensors (Basel, Switzerland) · 2023Review
- How Participatory Health Informatics Catalyzes One Digital Health.Yearbook of medical informatics · 2023Article
- Article
- Efficacy, Usability, and Acceptability of a Chatbot for Promoting COVID-19 Vaccination in Unvaccinated or Booster-Hesitant Young Adults: Pre-Post Pilot Study.Journal of medical Internet research · 2022Article
- Interventions to increase COVID-19 vaccine uptake: a scoping review.The Cochrane database of systematic reviews · 2022Article
- The Effectiveness of Interventions for Increasing COVID-19 Vaccine Uptake: A Systematic Review.Vaccines · 2022Review
- The Vaccination Process against the COVID-19: Opportunities, Problems andHealthcare (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 10 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a long history in Japan of public concerns about vaccine adverse events. Few studies have assessed how mobile messenger apps affect COVID-19 vaccine hesitancy.
methodsCorowa-kun, a free chatbot, was created on February 6, 2021 in LINE, the most popular messenger app in Japan. Corowa-kun provides instant, automated answers to 70 frequently asked COVID-19 vaccine questions. A cross-sectional survey with 21 questions was performed within Corowa-kun during April 5-12, 2021.
resultsA total of 59,676 persons used Corowa-kun during February-April 2021. Of them, 10,192 users (17%) participated in the survey. Median age was 55 years (range 16-97), and most were female (74%). COVID-19 vaccine hesitancy reported by survey respondents decreased from 41% to 20% after using Corowa-kun. Of the 20% who remained hesitant, 16% (1,675) were unsure, and 4% (364) did not intend to be vaccinated. Factors associated with vaccine hesitancy were: age 16-34 (odds ratio [OR] = 3.7; 95% confidential interval [CI]: 3.0-4.6, compared to age ≥ 65), female sex (OR = 2.4; Cl: 2.1-2.8), and history of a previous vaccine side-effect (OR = 2.5; Cl: 2.2-2.9). Being a physician (OR = 0.2; Cl: 0.1-0.4) and having received a flu vaccine the prior season (OR = 0.4; Cl: 0.3-0.4) were protective.
conclusionsA substantial number of people used the chabot in a short period. Mobile messenger apps could be leveraged to provide accurate vaccine information and to investigate vaccine intention and risk factors for vaccine hesitancy.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.