ArticleFertility and sterility2022
Geographic variation in semen parameters from data used for the World Health Organization semen analysis reference ranges.
Article in Fertility and sterility, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global trends in semen quality of young men: a systematic review and regression analysis.Journal of assisted reproduction and genetics · 2023Pooled it
- Temporal trends in equine sperm progressive motility: a systematic review and meta-regression.Reproduction (Cambridge, England) · 2023Pooled it
- Partner Ethnicity and Assisted Reproductive Technology Outcomes: A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Trends in semen parameters of infertile men in South Africa and Nigeria.Scientific reports · 2023Article
- No Evidence of Temporal Decline in Semen Parameters Over 17 Years Among Men Who Underwent Fertility Evaluation from Indian Southern States.American journal of men's healthArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study geographic variations in sperm parameters using data from the trials that defined the reference ranges of the World Health Organization 2021 manual.
designRetrospective evaluation of the data used to define the World Health Organization reference ranges.
settingNot applicable. PATIENT(S): Data from 11 studies, including 3,484 participants across 5 continents. INTERVENTION(S): The data were divided according to geographic locations. MAIN OUTCOME MEASURE(S): Differences in sperm parameters. RESULT(S): The semen volume was significantly lower in samples from Asia and Africa than in other regions. The sperm concentration was the lowest in Africa and highest in Australia. The total motile sperm count (TMSC) and total motile progressive sperm count (TMPS) were significantly lower in Africa than in other regions. The TMSC and TMPS in Asia and the United States were significantly lower than in Europe and Australia. The 5th percentile of the sperm concentration was lowest in the United States (12.5 × 10 CONCLUSION(S): Significant geographic differences in sperm parameters exist, and regional fertility societies should consider adding their own reference ranges on the basis of local experience and treatment outcomes.
Indexed as
Identifiers
35750517What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.