Evidence map›Paper›PMID 35750430›Full record

ArticleBMJ case reports2022

Allergy testing for Cremophor in a patient with cervical cancer with infusion reactions to paclitaxel and docetaxel.

Kazuho Nakanishi, Shizuka Okazaki, Go Ichikawa, Shunji Suzuki

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kazuho NakanishiObstetrics and Gynecology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan knakanishi@nms.ac.jp.ORCID http://orcid.org/0000-0002-3848-3752
Shizuka OkazakiDermatology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan.
Go IchikawaObstetrics and Gynecology, Nippon Medical School Chiba Hokusoh Hospital, Inzai-shi, Chiba, Japan.
Shunji SuzukiObstetrics and Gynecology, Nippon Medical School Hospital, Bunkyo-ku, Tokyo, Japan.
Chiba Hokusou Hospital · JPNippon Medical School Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A woman in her 30s with cervical cancer underwent postoperative chemotherapy and showed allergic reactions to multiple taxanes. As the patient had infusion reactions to both paclitaxel and docetaxel, a prick test with Cremophor was conducted. In the absence of an allergic reaction to etoposide, we determined that the patient was allergic to pure taxane compounds. Among infusion reactions caused by taxanes, Cremophor allergy is reported in 3% of cases. Therefore, a prick test with Cremophor performed on a taxane infusion reaction will be useful in diagnosing allergy. In addition, allergy due to docetaxel may be managed by adequate premedication and continuous intravenous chlorpheniramine administration.

Indexed as

HypersensitivityUterine Cervical NeoplasmsDocetaxelFemaleHumansPaclitaxelPolyethylene GlycolsTaxoidscremophorDocetaxelPaclitaxelPolyethylene GlycolsTaxoidsCervical cancerChemotherapyGynecological cancerObstetrics, gynaecology and fertilityUnwanted effects / adverse reactions

Identifiers

PMID35750430
PMCPMC9234805
OpenAlexW4283384295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.