Evidence map›Paper›PMID 35750337›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

Epigenetic Reprogramming Leads to Downregulation of CD4 and Functional Changes in African Green Monkey Memory CD4

Andrew R Rahmberg, Tovah E Markowitz, Joseph C Mudd, Vanessa Hirsch, Jason M Brenchley

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrew R RahmbergBarrier Immunity Section, Lab of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.ORCID 0000-0002-6306-4584
Tovah E MarkowitzNIAID Collaborative Bioinformatics Resource, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Joseph C MuddTulane National Primate Research Center, Division of Immunology, Tulane University, New Orleans, LA; and.
Vanessa HirschNonhuman Primate Virology Section, Lab of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.
Jason M BrenchleyBarrier Immunity Section, Lab of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD; jbrenchl@mail.nih.gov.ORCID 0000-0001-8357-2984
National Institutes of Health · USAmerican Medical Informatics Association · USTulane University · US

Funding

Infectious Diseases Research Technologies Core - BethesdaZICAI001051 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI CHERRY, JAMES · 2009 to 2025
$226.1M
Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Mechanisms of Immune Activation and Disease Progression in Animal ModelsZIAAI001029 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BRENCHLEY, JASON · 2009 to 2025
$28.2M
Role of RhCMV in shaping the SIV proviral landscapeR01AI167644 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI Joseph Christopher Mudd · 2022 to 2026
$4.3M
Mechanisms and Therapeutic Targeting of CD4 Down regulation in African Green MonkeysR21OD031229 · OD · TULANE UNIVERSITY OF LOUISIANA · PI MUDD, JOSEPH CHRISTOPHER · 2021 to 2022
$611k
Mechanisms of Immune Activation and Disease Progression in Animal ModelsZ01AI001029 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BRENCHLEY, JASON · 2008 to 2008
$455k
Intramural NIH HHS Z01 AI001029Intramural NIH HHS Z99 AI999999Intramural NIH HHS ZIA AI001029NIAID NIH HHS R01 AI167644NIH HHS P51 OD011104NIH HHS R21 OD031229
6 · The paper itself

Abstract

African green monkeys (AGMs),

Indexed as

Simian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsCD4-Positive T-LymphocytesChlorocebus aethiopsChromatinDown-RegulationEpigenesis, GeneticT-Lymphocytes, Helper-InducerT-Lymphocyte SubsetsChromatin

Identifiers

PMID35750337
PMCPMC9283288
OpenAlexW4283518693

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.