Evidence map›Paper›PMID 35750336›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2022

MAVS Expression in Alveolar Macrophages Is Essential for Host Resistance against

Xi Wang, Cristina Cunha, Madeleine S Grau, Shelly J Robertson, João F Lacerda, António Campos, Katrien Lagrou, Johan Maertens, Sonja M Best, Agostinho Carvalho and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Trans-Kingdom dsRNA Sensing:bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Recent developments inMicrobiology and molecular biology reviews : MMBR · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Interplay of Cytokines and Chemokines in Aspergillosis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  10. Multifaceted mitochondria in innate immunity.npj metabolic health and disease · 2024
    Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Xi WangDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH.ORCID 0000-0003-2152-9045
Cristina CunhaLife and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.
Madeleine S GrauDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH.
Shelly J RobertsonLaboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT.
João F LacerdaInstituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Lisbon, Portugal.ORCID 0000-0003-1351-2809
António CamposServiço de Transplantação de Medula Óssea, Instituto Português de Oncologia do Porto, Porto, Portugal.
Katrien LagrouDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.
Johan MaertensDepartment of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium.ORCID 0000-0003-4257-5980
Sonja M BestLaboratory of Virology, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT.
Agostinho CarvalhoLife and Health Sciences Research Institute, School of Medicine, University of Minho, Braga, Portugal.ORCID 0000-0001-8935-8030
Joshua J ObarDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Lebanon, NH; joshua.j.obar@dartmouth.edu.ORCID 0000-0003-4068-7911
Dartmouth College · USNational Institutes of Health · USRega Institute for Medical Research · BEUnited Nations University · PTIPO Porto · PTUniversity of Lisbon · PT

Funding

IMMUNOBIOLOGY OF MYELOID AND LYMPHOID CELLST32AI007363 · NIAID · DARTMOUTH COLLEGE · PI Claudia V Jakubzick · 1990 to 2026
$9.5M
TRANSLATIONAL RESEARCH COREP30GM106394 · NIGMS · DARTMOUTH COLLEGE · PI MADDEN, DEAN R · 2013 to 2017
$6.1M
Center for Molecular, Cellular, and Translational ImmunologyP30GM103415 · NIGMS · DARTMOUTH COLLEGE · PI GREEN, WILLIAM R · 2012 to 2015
$4.7M
Fungal spore sensing by MDA5 is necessary for antifungal immunity against Aspergillus fumigatusR01AI139133 · NIAID · DARTMOUTH COLLEGE · PI JOSHUA J OBAR · 2019 to 2026
$3.6M
NIAID NIH HHS R01 AI139133NIAID NIH HHS T32 AI007363NIGMS NIH HHS P30 GM103415NIGMS NIH HHS P30 GM106394
6 · The paper itself

Abstract

Our recent data demonstrate a critical role of the RIG-I-like receptor family in regulating antifungal immunity against

Indexed as

Aspergillus fumigatusInvasive Pulmonary AspergillosisAnimalsAntifungal AgentsDisease Models, AnimalHumansMacrophages, AlveolarMiceAntifungal Agents

Identifiers

PMID35750336
PMCPMC9307106
OpenAlexW4283523879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.