Evidence map›Paper›PMID 35749996›Full record

ArticleEnvironment international2022

Does short-term, airborne lead exposure during pregnancy affect birth outcomes? Quasi-experimental evidence from NASCAR's deleading policy.

Linda T M Bui, Ron Shadbegian, Alicia Marquez, Heather Klemick, Dennis Guignet

Open access · goldAbstract read
In one paragraph

Article in Environment international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Lead exposure at the feto-maternal interface: a cause for concern for fetal membrane trophoblasts.Toxicological sciences : an official journal of the Society of Toxicology · 2025
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Linda T M BuiDepartment of Economics, MS 021, Brandeis University, 415 South Street, Waltham, MA 02453, United States. Electronic address: ltbui@brandeis.edu.
Ron ShadbegianDepartment of Economics, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182, United States. Electronic address: rshadbegian@sdsu.edu.
Alicia MarquezJeb E. Brooks School of Public Policy, Martha Van Rensselaer Hall, Cornell University, Ithaca, NY 14853, United States. Electronic address: am2336@cornell.edu.
Heather KlemickUS Environmental Protection Agency, National Center for Environmental Economics, 1200 Pennsylvania Ave NW (MC 1809T), Washington, DC 20460, United States. Electronic address: Klemick.heather@epa.gov.
Dennis GuignetDepartment of Economics, Appalachian State University, 416 Howard Street, ASU Box 32051, Boone, NC 28608, United States. Electronic address: guignetdb@appstate.edu.
Appalachian State University · USBrandeis University · USCornell University · USEnvironmental Protection Agency · USSan Diego State University · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

backgroundThere is evidence of a weak placental-fetal barrier to lead, suggesting that maternal lead exposure could affect the fetus. The health consequences for newborns from in utero lead exposure are not well understood.

objectivesWe estimated the effects by trimester, of short-term (<1 week), airborne lead exposure during pregnancy on birth outcomes.

methodsWe use quasi-experimental variation in airborne lead exposure during pregnancy, based on NASCAR's deleading of racing fuel in 2007, in a difference-in-differences model, to estimate the effect of deleading on the birth outcomes of all live births (n = 147,673) in the Charlotte-Concord-Gastonia Metropolitan Statistical Area between 2004 and 2009.

resultsAfter deleading, children born to mothers residing <4000 m of Charlotte Motor Speedway (relative to those residing >10,000 m) experienced an average increase in birthweight (BW) of 102.50 g [P < 0.001]. The probability of low birthweight (LBW) declined by 0.045 [P = 0.001], preterm (PRE) births by 0.03 [P = 0.04], and small for gestational age (SGA) by 0.04 [P = 0.002]. We find that benefits accrue primarily in preterm LBW and SGA babies, and from decreased lead exposure in the first trimester.

conclusionsShort-term exposure to airborne lead during pregnancy adversely affects birth outcomes. Reducing even very brief exposure to airborne lead during pregnancy may improve birth outcomes.

Indexed as

Birth outcomesInfant healthLead exposureQuasi-experiment

Identifiers

PMID35749996
PMCPMC9829110
OpenAlexW4283077684

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.