Evidence map›Paper›PMID 35749000›Full record

ReviewDiscover oncology2022

Effect of gut microbiota in the colorectal cancer and potential target therapy.

Junchuan Li, Yuzhou Zhu, Lie Yang, Ziqiang Wang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Discover oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Effects of gut microbiota in breast cancer.Frontiers in oncology · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Junchuan Li *Gastrointestinal Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yuzhou Zhu *Gastrointestinal Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Lie YangGastrointestinal Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China. lie_222@163.com.
Ziqiang WangGastrointestinal Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China. wangziqiang@scu.edu.cn.

Funding

1·3·5 project for disciplines of excellence-Clinical Research Incubation Project, and West China Hospital, Sichuan University No. 2019HXFH0311.3.5 project for disciplines of excellence, West China Hospital, Sichuan University No. 20HXJS003Department of Science and Technology of Sichuan Province No. 2021YFS0025Ministry of Science and Technology of the People's Republic of China No. 2017YFC0908204
6 · The paper itself

Abstract

The symbiotic interaction between gut microbiota and the digestive tract is an important factor in maintaining the intestinal environment balance. Colorectal cancer (CRC) is a complex disease involving the interaction between tumour cells and a large number of microorganisms. The microbiota is involved in the occurrence, development and prognosis of colorectal cancer. Several microbiota species have been studied, such as Fusobacterium nucleatum (F. nucleatum), Enterotoxigenic Bacteroides fragilis (ETBF), Streptococcus bovis (S. bovis), Lactobacillus, and Bifidobacterium. Studies about the interaction between microbiota and CRC were retrieved from Embase, PubMed, Ovid and Web of Science up to 21 Oct 2021. This review expounded on the effect of microbiota on CRC, especially the dysregulation of bacteria and carcinogenicity. The methods of gut microbiota modifications representing novel prognostic markers and innovative therapeutic strategies were also described.

Indexed as

Colorectal cancerGut dysbiosisGut microbiotaMethylationPathogenesisTumor proliferation

Identifiers

PMID35749000
PMCPMC9232688

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.