Evidence map›Paper›PMID 35748863›Full record

ArticleeLife2022

Cd59 and inflammation regulate Schwann cell development.

Ashtyn T Wiltbank, Emma R Steinson, Stacey J Criswell, Melanie Piller, Sarah Kucenas

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Molecular characterization ofOpen veterinary journal · 2026
    Article
  3. Article
  4. Article
  5. Inflammation in Development and Aging: Insights from the Zebrafish Model.International journal of molecular sciences · 2024
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashtyn T WiltbankNeuroscience Graduate Program, University of Virginia, Charlottesville, United States.
Emma R SteinsonDepartment of Biology, University of Virginia, Charlottesville, United States.
Stacey J CriswellDepartment of Cell Biology, University of Virginia, Charlottesville, United States.
Melanie PillerDepartment of Biology, University of Virginia, Charlottesville, United States.
Sarah KucenasNeuroscience Graduate Program, University of Virginia, Charlottesville, United States.ORCID 0000-0002-1950-751X
University of Virginia · US

Funding

Characterization of the cellular and molecular mechanisms that mediate glial tilingR01NS107525 · NINDS · UNIVERSITY OF VIRGINIA · PI KUCENAS, SARAH C · 2019 to 2023
$1.7M
Elucidating glial diversity in the peripheral nervous systemR21NS124164 · NINDS · UNIVERSITY OF VIRGINIA · PI KUCENAS, SARAH C · 2021 to 2021
$444k
NINDS NIH HHS R01 NS107525NINDS NIH HHS R21 NS124164
6 · The paper itself

Abstract

Efficient neurotransmission is essential for organism survival and is enhanced by myelination. However, the genes that regulate myelin and myelinating glial cell development have not been fully characterized. Data from our lab and others demonstrates that

Indexed as

Myelin SheathZebrafishAnimalsCD59 AntigensInflammationOligodendrogliaSchwann CellsCD59 AntigensCD59complementdevelopmental biologyinflammationmyelinneurosciencenode of RanvierSchwann cellzebrafish

Identifiers

PMID35748863
PMCPMC9232220
OpenAlexW4283370137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.