ArticleInternational journal of methods in psychiatric research2022
Further validation of the THINC-it tool and extension of the normative data set in a study of n = 10.019 typical controls.
Article in International journal of methods in psychiatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- Functional connectivity correlates of reaction time variability in treatment-resistant major depression.Psychological medicine · 2026Article
- Sleep, Steps, and Screens: Between- and within-person effects of digital markers of daily life behaviors on smartphone-based assessments of cognitive functioning in depression.Neuroscience applied · 2026Article
- The association between obstructive sleep apnea and total cerebral small vessel disease burden-Neurovascular insights of OSA.Frontiers in neuroscience · 2026Article
- Locus Coeruleus MR Measured Signal Intensity in Fibromyalgia Relative to Healthy Controls.European journal of pain (London, England) · 2025Article
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- The Association Between Cognitive Functioning and Depression Severity: A Multiwave Longitudinal Remote Assessment Study.Depression and anxiety · 2025Article
- Successful treatment with guanfacine in a long-COVID case manifesting marked cognitive impairment.Neuropsychopharmacology reports · 2024Article
- Tablet-Based Cognitive and Eye Movement Measures as Accessible Tools for Schizophrenia Assessment: Multisite Usability Study.JMIR mental health · 2024Article
- The association between persistent cognitive difficulties and depression and functional outcomes in people with major depressive disorder.Psychological medicine · 2023Observational
- Further validation of the THINC-it tool and extension of the normative data set in a study of n = 10.019 typical controls.International journal of methods in psychiatric research · 2022Article
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4 authors.
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Abstract
introductionWe report further validation and normative data for the THINC-Integrated Tool (THINC-it), a measure of cognitive function designed for use with individuals living with Major Depressive Disorder, but which is finding use in further psychiatric and neurological diseases. THINC-it comprises four objective computerised cognitive tests based on traditional psychological paradigms and a version of the Perceived Deficits Questionnaire assessment.
methodsSample size of n = 10.019 typical control study participants were tested on one to two occasions to further validate the reliability of THINC-it. Temporal reliability was assessed across 120-180 days.
resultsTest-retest reliability correlations varied between r = 0.50 and 0.72 for the component measures and r = 0.75 (95% confidence intervals 0.74, 0.76) for the THINC-it composite score. Normative data categorised by Age, Sex and Years of Education were calculated and the effect on task performance was reported. DISCUSSION: Our analysis confirms previously reported levels of reliability and validates previously reported normative data values.
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