ArticleBrain and behavior2022
Hypersensitive C-reactive protein-albumin ratio is associated with stroke-associated pneumonia and early clinical outcomes in patients with acute ischemic stroke.
Article in Brain and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- European stroke organisation guideline on stroke-associated pneumonia.European stroke journal · 2026Guideline
- Prognostic value of the C-reactive protein to albumin ratio in patients with stroke: a meta-analysis.Scientific reports · 2025Pooled it
- Stroke-Associated Pneumonia and Impaired Functional Recovery After Stroke: The Role of Nutritional-Inflammatory Factors.Advances in respiratory medicine · 2026Article
- Risk estimation for stroke-associated pneumonia in acute ischemic stroke: a nomogram-based approach.Arquivos de neuro-psiquiatria · 2026Article
- C-reactive protein-to-albumin ratio predicts intensive care admission and disease severity in autoimmune encephalitis.Frontiers in immunology · 2026Article
- C-reactive protein to albumin ratio and Glasgow Coma Scale score as the predictors for weaning outcomes in traumatic brain injury.Annals of medicine · 2025Article
- The impact of post-stroke pneumonia on survival and functional outcomes: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Higher C-reactive protein/albumin ratio is a potential marker for predicting amputation in patients with diabetic foot infection.Archives of endocrinology and metabolism · 2025Review
- Dynamic Trends of Albumin-to-C-Reactive Protein Ratio: A Prognostic Indicator in Elderly Patients with Community-Acquired Pneumonia.Journal of inflammation research · 2025Article
- Association between C-reactive protein/albumin ratio and mortality in older Japanese patients with post-stroke dysphagia.Frontiers in neurology · 2025Article
- Prediction of Antibiotic Efficacy in Cerebral Hemorrhage-Associated Pneumonia Using Inflammatory Hematological Indices: A Retrospective Study.Journal of inflammation research · 2025Article
- Predictive Value of Inflammatory Scores for Left Atrium Thrombosis in Ischemic Stroke Without Atrial Fibrillation.Medicina (Kaunas, Lithuania) · 2024Article
- Identification of risk factors and construction of a nomogram predictive model for post-stroke infection in patients with acute ischemic stroke.World journal of clinical cases · 2024Article
- Article
- The clinical value of nutritional and inflammatory indicators in predicting pneumonia among patients with intracerebral hemorrhage.Scientific reports · 2024Article
- The Association between High Mobility Group Box 1 and Stroke-Associated Pneumonia in Acute Ischemic Stroke Patients.Brain sciences · 2022Article
- Hypersensitive C-reactive protein-albumin ratio is associated with stroke-associated pneumonia and early clinical outcomes in patients with acute ischemic stroke.Brain and behavior · 2022Article
- Inflammatory response biomarkers nomogram for predicting pneumonia in patients with spontaneous intracerebral hemorrhage.Frontiers in neurology · 2022Article
- C-reactive protein to albumin ratio as a novel predictor of stroke-associated pneumonia: a retrospective cohort study revealing non-linear threshold effects.Frontiers in neurologyArticle
- A narrative review of neuroprotective effects of albumin: The underlying mechanisms and therapeutic prospects in ischemic stroke.Brain circulationReview
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe aimed to explore the association between the baseline hypersensitive C-reactive protein-albumin ratio (CAR) and stroke-associated pneumonia (SAP) during hospitalization and the short-term prognosis in patients with acute ischemic stroke (AIS).
methodsWe enrolled 766 patients with AIS and collected their admission baseline characteristics, including their National Institutes of Health Stroke Scale score, CAR, age, atrial fibrillation, dysphagia, sex, stroke severity (A
resultsDuring hospitalization, 92 (11.9%) patients were diagnosed with SAP. The patients with SAP had a higher CAR than the non-SAP patients (p < .001). In the multivariate-adjusted model, the patients in the Q3 and Q4 groups had a higher SAP risk (aOR was 5.21 and 17.72, p-trend < .001) than those in the lowest quartile. The area under the curve for the CAR's ability to predict SAP was 0.810 in the receiver operating characteristic curve analysis and had a similar predictive efficacy as the A
conclusionsPatients with AIS with a high CAR at admission are more likely to develop SAP during hospitalization and have poor short-term clinical outcomes. These findings might help to timely identify patients at high risk of SAP and provide a basis for further research on prophylactic antibiotic therapy.
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