Evidence map›Paper›PMID 35748091›Full record

ArticlePhysiological reports2022

The impact of daytime transoral neuromuscular stimulation on upper airway physiology - A mechanistic clinical investigation.

Brandon Nokes, Christopher N Schmickl, Rebbecca Brena, Nana Naa-Oye Bosompra, Dillon Gilbertson, Scott A Sands, Rakesh Bhattacharjee, Dwayne L Mann, Robert L Owens, Atul Malhotra and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Benefit of adjunctive transoral neuromuscular electrical stimulation with positive airway pressure therapy: a case report.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2023
    Article
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Brandon NokesUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.ORCID 0000-0003-3515-7545
Christopher N SchmicklUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.ORCID 0000-0001-5417-9980
Rebbecca BrenaUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.
Nana Naa-Oye BosompraUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.
Dillon GilbertsonUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.
Scott A SandsDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Rakesh BhattacharjeeRady's Children's Hospital, San Diego, California, USA.
Dwayne L MannInstitute for Social Science Research, University of Queensland, Brisbane, Australia.
Robert L OwensUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.
Atul MalhotraUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.
Jeremy E OrrUniversity of California, Division of Pulmonary, Critical Care, Sleep Medicine, and Physiology, La Jolla, California, USA.
University of California System · USBrigham and Women's Hospital · USFleet Science Center · USRady Children's Hospital-San Diego · USThe University of Queensland · AU

Funding

Training in the Next Generation in Respiratory ScienceT32HL134632 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MALHOTRA, ATUL, POWELL, FRANK L. · 2017 to 2021
$2.1M
NHLBI NIH HHS T32 HL134632
6 · The paper itself

Abstract

There is a need for alternatives to positive airway pressure for the treatment of obstructive sleep apnea and snoring. Improving upper airway dilator function might alleviate upper airway obstruction. We hypothesized that transoral neuromuscular stimulation would reduce upper airway collapse in concert with improvement in genioglossal muscle function. Subjects with simple snoring and mild OSA (AHI < 15/h on screening) underwent in-laboratory polysomnography with concurrent genioglossal electromyography (EMGgg) before and after 4-6 weeks of twice-daily transoral neuromuscular stimulation. Twenty patients completed the study: Sixteen males, mean ± SD age 40 ± 13 years, and BMI 26.3 ± 3.8 kg/m

Indexed as

Sleep Apnea, ObstructiveSnoringAdultElectromyographyHumansMaleMiddle AgedPolysomnographyTongue

Identifiers

PMID35748091
PMCPMC9226850
OpenAlexW4283399520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.