Evidence map›Paper›PMID 35748080›Full record

ArticleYonsei medical journal2022

Re-Assessment of Applicability of Greulich and Pyle-Based Bone Age to Korean Children Using Manual and Deep Learning-Based Automated Method.

Jisun Hwang, Hee Mang Yoon, Jae-Yeon Hwang, Pyeong Hwa Kim, Boram Bak, Byeong Uk Bae, Jinkyeong Sung, Hwa Jung Kim, Ah Young Jung, Young Ah Cho and 1 more

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
12.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Jisun HwangDepartment of Radiology, Hallym University Dongtan Sacred Heart Hospital, Hwaseong, Korea.ORCID https://orcid.org/0000-0002-7593-2246
Hee Mang YoonDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. espoirhm@gmail.com.ORCID https://orcid.org/0000-0001-6491-5734
Jae-Yeon HwangDepartment of Radiology, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, College of Medicine, Pusan National University, Yangsan, Korea. jyhwang79@gmail.com.ORCID https://orcid.org/0000-0003-2777-3444
Pyeong Hwa KimDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-4276-8803
Boram BakUniversity of Ulsan Foundation for Industry Cooperation, Ulsan, Korea.ORCID https://orcid.org/0000-0003-0409-6292
Byeong Uk BaeVUNO, Inc., Seoul, Korea.ORCID https://orcid.org/0000-0003-2309-8517
Jinkyeong SungVUNO, Inc., Seoul, Korea.ORCID https://orcid.org/0000-0003-3546-6081
Hwa Jung KimDepartment of Clinical Epidemiology and Biostatistics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-1916-7014
Ah Young JungDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7427-6240
Young Ah ChoDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-6722-121X
Jin Seong LeeDepartment of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-8470-4595
Ulsan College · KRPusan National University Yangsan Hospital · KRUniversity of Ulsan · KR

Funding

Asan Medical Center Children's Hospital 2020IE0016-1National Research Foundation of Korea 2020R1G1A1004591
6 · The paper itself

Abstract

purposeTo evaluate the applicability of Greulich-Pyle (GP) standards to bone age (BA) assessment in healthy Korean children using manual and deep learning-based methods. MATERIALS AND

methodsWe collected 485 hand radiographs of healthy children aged 2-17 years (262 boys) between 2008 and 2017. Based on GP method, BA was assessed manually by two radiologists and automatically by two deep learning-based BA assessment (DLBAA), which estimated GP-assigned (original model) and optimal (modified model) BAs. Estimated BA was compared to chronological age (CA) using intraclass correlation (ICC), Bland-Altman analysis, linear regression, mean absolute error, and root mean square error. The proportion of children showing a difference >12 months between the estimated BA and CA was calculated.

resultsCA and all estimated BA showed excellent agreement (ICC ≥0.978,

conclusionContemporary healthy Korean children showed different rates of skeletal development than GP standard-BA, and systemic bias should be considered when determining children's skeletal maturation.

Indexed as

Age Determination by SkeletonDeep LearningAgedAsian PeopleChildHumansMaleRadiographyRepublic of KoreaAge determination by skeletonchilddeep learninghand bonesradiography

Identifiers

PMID35748080
PMCPMC9226834
OpenAlexW4283455909

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.