ArticleActa anaesthesiologica Scandinavica2022
Long-term cognitive and functional status in Danish ICU patients with COVID-19.
Article in Acta anaesthesiologica Scandinavica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Health-related quality of life in COVID-19 patients: a systematic review and meta-analysis of EQ-5D studies.Health and quality of life outcomes · 2025Pooled it
- Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025Pooled it
- Health-Related Quality of Life One Year After Intensive Care Unit Admission for COVID-19: A Retrospective, Cross-Sectional, Longitudinal Observational Study.Health science reports · 2025Article
- Health outcomes of COVID-19 patients from Wuhan, China 3-year after hospital discharge: a cohort study.BMJ open · 2024Observational
- In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization.JAMA network open · 2024Article
- Neurocognitive and Neuropsychiatric Sequelae in Long COVID-19 Infection.Brain sciences · 2024Article
- Health-Related Quality of Life Improves in Parallel with FEV1 and 6-Minute Walking Distance Test at Between 3 and 12 Months in Critical COVID-19 Survivors.American journal of medicine open · 2023Article
- Long-term survival after intensive care for COVID-19: a nationwide cohort study of more than 8000 patients.Annals of intensive care · 2023Article
- [Quality of life and functional status at hospital discharge of patients with COVID-19 in Colombia].Revista de salud publica (Bogota, Colombia) · 2023Article
- Review
- COVID-19 Accelerated Cognitive Decline in Elderly Patients with Pre-Existing Dementia Followed up in an Outpatient Memory Care Facility.Journal of clinical medicine · 2023Article
- Article
- Cognitive Impairment after Post-Acute COVID-19 Infection: A Systematic Review of the Literature.Journal of personalized medicine · 2022Review
- Long-term cognitive and functional status in Danish ICU patients with COVID-19.Acta anaesthesiologica Scandinavica · 2022Article
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27 authors.
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Abstract
backgroundICU admission due to COVID-19 may result in cognitive and physical impairment. We investigated the long-term cognitive and physical status of Danish ICU patients with COVID-19.
methodsWe included all patients with COVID-19 admitted to Danish ICUs between March 10 and May 19, 2020. Patients were the contacted prospectively at 6 and 12 months for follow-up. Our primary outcomes were cognitive function and frailty at 6 and 12 months after ICU admission, estimated by the Mini Montreal Cognitive Assessment, and the Clinical Frailty Scale. Secondary outcomes were 6- and 12-month mortality, health-related quality of life (HRQoL) assessed by EQ-5D-5L, functional status (Barthel activities of daily living and Lawton-Brody instrumental activities of daily living), and fatigue (Fatigue Assessment Scale). The study had no information on pre-ICU admission status for the participants.
resultsA total of 326 patients were included. The 6- and 12-month mortality was 37% and 38%, respectively. Among the 204 six-month survivors, 105 (51%) participated in the 6-month follow-up; among the 202 twelve-month survivors, 95 (47%) participated in the 12-month follow-up. At 6 months, cognitive scores indicated impairment for 26% (95% confidence interval [CI], 11.4-12.4) and at 12 months for 17% (95% CI, 12.0-12.8) of participants. Frailty was indicated in 20% (95% CI, 3.4-3.9) at 6 months, and for 18% (95% CI, 3.3-3.8) at 12 months. Fatigue was reported by 52% at 6 months, and by 47% at 12 months. For HRQoL, moderate, severe, or extreme health problems were reported by 28% at 6 months, and by 25% at 12 months.
conclusionLong-term cognitive, functional impairment was found in up to one in four of patients surviving intensive care for COVID-19. Fatigue was present in nearly half the survivors at both 6 and 12 months. However, pre-ICU admission status of the patients was unknown.
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