Evidence map›Paper›PMID 35747979›Full record

SynthesisCurrent cardiology reviews2023

Incidence, Current Guidelines and Management of Gastrointestinal Bleeding after Transcatheter Aortic Valve Replacement: A Systematic Review.

Devina Adalja, Harshvardhan Zala, Varun Victor, Aakash Sheth, Charles Willyard, Emi Suzuki, Harsh P Patel, Monil Majmundar, Saraschandra Vallabhajosyula, Rajkumar Doshi

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Current cardiology reviews, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Devina AdaljaDepartment of Internal Medicine, St Joseph\'s University Medical Center, Paterson, NJ, USA.
Harshvardhan ZalaDepartment of Clinical Research, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Varun VictorDepartment of Internal Medicine, Canton Medical Education Foundation, Canton, OH, USA.
Aakash ShethDepartment of Internal Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, USA.
Charles WillyardDepartment of Internal Medicine, University of Nevada Reno School of Medicine, Reno, NV, USA.
Emi SuzukiDepartment of Pediatrics, UCSF- Fresno, Fresno, CA, USA.
Harsh P PatelDepartment of Internal Medicine, Louis A Weiss Memorial Hospital, Chicago, IL, USA.
Monil MajmundarDepartment of Cardiology, Maimonides Medical Center, Brooklyn, New York, USA.
Saraschandra VallabhajosyulaSection of Cardiovascular Medicine, Wake Forest University School of Medicine, Winston- Salem, NC, USA.
Rajkumar DoshiDepartment of Cardiology, St Joseph\'s University Medical Center, Paterson, NJ, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is a significant increase in morbidity and mortality in patients complicated by major bleeding following transcatheter aortic valve replacement (TAVR). It has become more challenging to manage such complications when the patient needs to be on anticoagulation or antiplatelet agent post-procedure to prevent thrombotic/embolic complications.

methodsWe systematically reviewed all available randomized controlled trials and observational studies to identify incidence rates of gastrointestinal bleeding post-procedure. After performing a systematic search, a total of 8731 patients from 15 studies (5 RCTs and 10 non-RCTs) were included in this review.

resultsThe average rate of gastrointestinal bleeding during follow-up was 3.0% in randomized controlled trials and 1.9% among observational studies.

conclusionGastrointestinal bleeding has been noted to be higher in the RCTs as compared to observational studies. This review expands knowledge of current guidelines and possible management of patients undergoing TAVR.

Indexed as

Aortic Valve StenosisTranscatheter Aortic Valve ReplacementAortic ValveGastrointestinal HemorrhageHumansIncidenceRisk FactorsTreatment Outcomeanticoagulationantiplateletgastrointestinal bleedingreviewTAVRTranscatheter aortic valve implantation

Identifiers

PMID35747979
PMCPMC10201885

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.