Evidence map›Paper›PMID 35747795›Full record

ArticleFrontiers in oncology2022

Reduced Dose Intensity of Daunorubicin During Remission Induction for Low-Risk Patients With Acute Lymphoblastic Leukemia: A Retrospective Cohort Study of the Chinese Children's Cancer Group.

Yong Zhuang, Kefei Wu, Xiaofan Zhu, Jiaoyang Cai, Shaoyan Hu, Ju Gao, Hua Jiang, Xiaowen Zhai, Xin Tian, Yongjun Fang and 13 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. [Optimized treatment of childhood B-lineage acute lymphoblastic leukemia].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 20 institutions in 1 country.

Yong ZhuangDepartment of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.
Kefei WuNational Children's Medical Center, Department of Hematology/Oncology, Key Laboratory of Pediatric Hematology and Oncology of China Ministry of Health, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiaofan ZhuState Key Laboratory of Experimental Hematology and Division of Pediatric Blood Diseases Center, Institute of Hematology and Blood Diseases Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Tianjin, China.
Jiaoyang CaiNational Children's Medical Center, Department of Hematology/Oncology, Key Laboratory of Pediatric Hematology and Oncology of China Ministry of Health, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shaoyan HuDepartment of Hematology/Oncology, Children's Hospital of Soochow University, Suzhou, China.
Ju GaoDepartment of Pediatrics, Key Laboratory of Birth Defects and Related Disease of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, China.
Hua JiangDepartment of Hematology/Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Xiaowen ZhaiDepartment of Hematology/Oncology, Children's Hospital of Fudan University, Shanghai, China.
Xin TianDepartment of Hematology/Oncology, Kunming Children's Hospital, Kunming, China.
Yongjun FangDepartment of Hematology/Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Runming JinDepartment of Pediatrics, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Qun HuDepartment of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hui JiangDepartment of Hematology/Oncology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Ningling WangDepartment of Pediatrics, Anhui Medical University Second Affiliated Hospital, Hefei, China.
Lirong SunDepartment of Pediatrics, Affiliated Hospital of Qingdao University, Qingdao, China.
Wing Kwan LeungDepartment of Pediatrics, Hong Kong Children's Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Minghua YangDepartment of Pediatrics, Xiangya Hospital Central South University, Changsha, China.
Kaili PanDepartment of Hematology/Oncology, Xi'an Northwest Women and Children Hospital, Xi'an, China.
Xuedong WuDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Changda LiangDepartment of Hematology/Oncology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Shuhong ShenNational Children's Medical Center, Department of Hematology/Oncology, Key Laboratory of Pediatric Hematology and Oncology of China Ministry of Health, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jie YuDepartment of Hematology/Oncology, Chongqing Medical University Affiliated Children's Hospital, Chongqing, China.
Xiuli JuDepartment of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.
Shanghai Jiao Tong University · CNQilu Hospital of Shandong University · CNAffiliated Hospital of Qingdao University · CNCentral South University · CNChildren's Hospital of Chongqing Medical University · CNChildren's Hospital of Fudan University · CNChinese University of Hong Kong · CNGuangzhou Women and Children Medical Center · CNInstitute of Hematology & Blood Diseases Hospital · CNJiangxi Provincial Children's Hospital · CNKunming Children's Hospital · CNNanfang Hospital · CNNorthwest Women's and Children's Hospital · CNSecond Affiliated Hospital of Nanjing Medical University · CNSecond Hospital of Anhui Medical University · CNShanghai Children's Medical Center · CNSichuan University · CNSoochow University · CNTongji Hospital · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is urgently necessary to reduce the adverse effects of chemotherapy while maintaining their cure high rates for children with acute lymphoblastic leukemia (ALL). The present study aimed to determine whether the dose intensity of daunorubicin during the remission-induction phase could be reduced for low-risk patients with ALL. A total of 2396 eligible patients, who participated in CCCG-ALL-2015 study and were provisionally assigned to the low-risk group, were included and divided into single-dose group and double-dose group according to the dosage of daunorubicin during the remission-induction phase. For patients with Clinical Trial Registration: http://www.chictr.org.cn/showproj.aspx?proj=10115, identifier ChiCTR-IPR-14005706.

Indexed as

acute lymphoblastic leukemiachildrendaunorubicinmulticenter studyremission-induction

Identifiers

PMID35747795
PMCPMC9209708
OpenAlexW4281721958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.