Evidence map›Paper›PMID 35747552›Full record

ArticleNeurology. Clinical practice2022

Cerebral White Matter Injury in a Newborn Infant With COVID-19: A Case Report.

Lucas Alves, Thaís Alcântara, Adriano Hazin, Leandro Lucato, Jurandy Júnior Ferraz de Magalhães, Joao Alves, Jucille Meneses

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Lucas AlvesDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Thaís AlcântaraDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Adriano HazinDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Leandro LucatoDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Jurandy Júnior Ferraz de MagalhãesDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Joao AlvesDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Jucille MenesesDepartment of Neuropediatric (LA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Neonatology (TA, JM), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (AH), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP); Department of Radiology (LL), Hospital das Clínicas da Universidade de São Paulo; Department of Virology (JJFM), Pernambuco State Central Laboratory (LACEN/PE); and Department of Pediatrics (JA), Instituto de Medicina Integral Prof. Fernando Figueira (IMIP), Recife, Brazil.
Instituto de Medicina Integral Professor Fernando Figueira · BRState Laboratory · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because the COVID-19 pandemic evolves, reports of neurologic manifestations and neuroimaging associated with SARS-CoV-2 have been reported in children and in neonates, although very few when compared with adults. Objectives: To describe a 3-day-old neonate presenting afebrile seizures with a persistent positive nasopharyngeal swab for SARS-CoV-2 and neuroimaging demonstrating extensive cerebral white matter injury. Methods: Consent was obtained to report this case. SARS-CoV-2 was tested using real-time reverse transcriptase-polymerase chain reaction amplification of virus acid from a nasopharyngeal swab. MRI of the brain was performed using axial T1, T2, fluid-attenuated inversion recovery, diffusion-weighted imaging, and T1 postcontrast sequences. Results: Brain MRI showed restricted diffusion in the periventricular white matter, subcortical white matter, and splenium of the corpus callosum. Discussion: Neurologic presentation of SARS-CoV-2 in newborns seems to be rare and is not fully known. SARS-CoV-2 infection should be considered in newborns with seizures and white matter abnormalities.

Identifiers

PMID35747552
PMCPMC9208415
OpenAlexW4281394423

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.