ArticleTherapeutic advances in neurological disorders2022
Association between systolic blood pressure parameters and unexplained early neurological deterioration (UnND) in acute ischemic stroke patients treated with mechanical thrombectomy.
Article in Therapeutic advances in neurological disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 7 citations in OpenAlex.
- SPRINFrontiers in neurology · 2026Article
- Eosinophils differentially affect early and delayed neurological deterioration after mechanical thrombectomy in stroke.BMC neuroscience · 2025Article
- Impact of Systolic Blood Pressure Trajectories and Variability on Unexplained Early Neurological Deterioration Post-Endovascular Treatment in Acute Ischemic Stroke Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2025Observational
- Risk Factors and Prognosis of Early Neurological Deterioration after Bridging Therapy.Current neurovascular research · 2024Article
- CNS-LAND score: predicting early neurological deterioration after intravenous thrombolysis based on systemic responses and injury.Frontiers in neurology · 2023Article
- Mean systolic blood pressure upon admission and clinical outcomes after endovascular treatment in patients with large vessel occlusion beyond 24 hours.Frontiers in neurologyArticle
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
Background: Neurological deterioration (ND) after mechanical thrombectomy (MT) of acute ischemic stroke (AIS) in anterior circulation is an important complication associated with a poor outcome. Moreover, evident causes of ND may remain unexplained (UnND). Objective: We sought to evaluate the association of the systolic blood pressure (SBP) parameters before MT, during MT, and during a 24-h period after MT with UnND. Methods: We analyzed 382 MT-treated AIS patients in two stroke centers from 2017 to 2019. The patients with unsuccessful recanalization and/or with symptomatic intracerebral hemorrhage after MT were excluded. Multivariate logistic regression analysis was used to identify the SBP parameters that predict UnND. Results: There were 5.9% patients with UnND within 24 h after MT among patients with successful recanalization what comprises 4.9% of all patients who had undergone MT. SBP > 180 mmHg on admission (odds ratio (OR): 4, 95% confidence interval (CI): 1.6-10, Conclusion: The association between the SBP parameters and UnND depends on the treatment period and the time of UnND occurrence. The J/U resembling relationship between SBP and UnEND was established during a 24-h period after MT.
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