Evidence map›Paper›PMID 35747222›Full record

ArticleThe British journal of cardiology2020

DOACs for stroke prevention in patients with AF and cancer.

Dipal Mehta, Daniel M Jones, Avirup Guha, Peter K MacCallum, Amitava Banerjee, Charlotte Manisty, Thomas Crake, Mark Westwood, Arjun K Ghosh

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The British journal of cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Dipal MehtaClinical Haematology, Barts Cancer Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, EC1A 7BE.
Daniel M JonesCardiology, Barts Cancer Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, EC1A 7BE.
Avirup GuhaAssistant Professor in Cardiology, Harrington Heart and Vascular Institute, Case Western Reserve University, Cleveland, OH 44106 USA.
Peter K MacCallumConsultant Haematologist, Thrombosis Service, Barts Health NHS Trust, London, EC1A 7BE.
Amitava BanerjeeHonorary Consultant Cardiologist, Institute of Health Informatics, University College London and Barts Health NHS Trust, London, EC1A 7BE.
Charlotte ManistyConsultant Cardiologist, Cardio-Oncology Service, Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, EC1A 7BE.
Thomas CrakeConsultant Cardiologist, Cardio-Oncology Service, Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, EC1A 7BE.
Mark WestwoodConsultant Cardiologist, Cardio-Oncology Service, Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, EC1A 7BE.
Arjun K GhoshConsultant Cardiologist, Cardio-Oncology Service, Barts Heart Centre, St. Bartholomew's Hospital, Barts Health NHS Trust, London, EC1A 7BE.
St Bartholomew's Hospital · GBBarts Health NHS Trust · GBCase Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke prophylaxis in atrial fibrillation is an important consideration in patients with cancer. However, there is little consensus on the choice of anticoagulation, due to the numerous difficulties associated with active cancer. Direct oral anticoagulants (DOACs) have been shown to be a promising option. Here, we conduct a simple cross-sectional analysis of 29 cancer patients receiving DOACs for stroke prophylaxis in atrial fibrillation at a tertiary-care institution in London. Our study demonstrates an encouraging efficacy and safety profile of DOACs used in this setting. We conclude by suggesting that, while DOACs may be useful, anticoagulation in cancer patients should continue to be individualised.

Indexed as

atrial fibrillationcancerdirect oral anticoagulants (DOACs)

Identifiers

PMID35747222
PMCPMC9205240
OpenAlexW4250837504

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.