ArticleInternational journal of dentistry2022
Efficacy of Low-Level Laser Therapy in Reducing Pain in the Initial Stages of Orthodontic Treatment.
Article in International journal of dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 19 citations in OpenAlex.
- Research Hotspots and Emerging Trends of Orthodontic-Related Discomfort and Pain: A Bibliometric Review.Pain research & management · 2025Pooled it
- Effect of chewing gum on orthodontic pain in patients receiving fixed orthodontic treatment: a systematic review and meta-analysis.European journal of medical research · 2023Pooled it
- Pulsed Nd:YAG versus continuous-wave laser photobiomodulation for orthodontic pain: a split-mouth RCT.Lasers in medical science · 2026Trial
- Efficacy of a simplified photobiomodulation protocol in orthodontic patients: a randomized crossover clinical trial.Dental press journal of orthodontics · 2026Trial
- Effect of led photobiomodulation on tooth movement, gingival hypertrophy and pain in response to treatment with fixed orthodontic appliance.Lasers in medical science · 2025Trial
- Efficacy of Different Regimens of 980 nm Low-Level Laser Therapy to Reduce Pain Caused by Elastomeric Separator Placement in Adults: A Randomized, Double-Blind, Split-Mouth Placebo-Controlled Study.Journal of clinical medicine · 2026Article
- Immune Responses in Orthodontic Treatment.Advances in experimental medicine and biology · 2026Review
- Effect of Laser Photobiomodulation on Postoperative Pain After Single-Visit Endodontic Treatment in Children: A Randomized Control Trial.Children (Basel, Switzerland) · 2024Article
- The Effect of Low-Level Laser Therapy on Accelerating Tooth Movement in Orthodontic Patients: A Randomized Controlled Trial.Journal of pharmacy & bioallied sciences · 2024Article
- Article
- Effect of low-level laser therapy in wound healing of primary molar teeth extraction.BMC oral health · 2024Article
- Low-Level Laser Therapy for Acute Pain: A Comprehensive Review.Current pain and headache reports · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: There is no consensus about the mechanism and efficacy in alleviating pain of the lower-level laser therapy (LLLT) during orthodontic treatment. This study aimed to evaluate the LLLT effectiveness clinically in reducing pain caused by orthodontic movement that occurs in the early stages of treatment. Methods: The sample consisted of 54 patients in need of orthodontic treatment divided into two groups. A 28 experimental patients group (initial mean age: 26.84 years old) was undergone gallium-aluminum-arsenide infrared laser application on 12 points for each tooth immediately after the installation of the first alignment archwire, and a 26 patients control group (initial mean age: 29.13 years old) was undergone to no pain control intervention at all. Pain intensity was measured by using a visual analog scale, which was marked pain level (mm) reported in 06, 24, 48, and 72 hours. The perception of pain (beginning, peak, decline, and absence) was evaluated by filling up a questionnaire. To compare the intensity and perception of pain between groups, a nonparametric Mann-Whitney has been performed. Results: The experimental group showed levels (mm) at 6 ( Conclusion: Low-level laser therapy is effective in reducing pain severity caused by orthodontic forces activation, and it promotes the analgesic action lasting effect during the most painful feeling time.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.