Evidence map›Paper›PMID 35746919›Full record

ReviewRSC advances2020

Bromodomain and BET family proteins as epigenetic targets in cancer therapy: their degradation, present drugs, and possible PROTACs.

Mohd Muddassir, Kunjal Soni, Chetan B Sangani, Abdullah Alarifi, Mohd Afzal, Naaser A Y Abduh, Yongtao Duan, Poonam Bhadja

Abstract readReview
In one paragraph

Review in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. PROTACs for BRDs proteins in cancer therapy: a review.Journal of enzyme inhibition and medicinal chemistry · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohd MuddassirDepartment of Chemistry, College of Science, King Saud University Riyadh 11451 KSA.ORCID https://orcid.org/0000-0001-7069-2557
Kunjal SoniShri Maneklal M. Patel Institute of Sciences and Research, Kadi Sarva Vishwavidyalaya University Gandhinagar Gujarat 382024 India.ORCID https://orcid.org/0000-0001-7197-3369
Chetan B SanganiShri Maneklal M. Patel Institute of Sciences and Research, Kadi Sarva Vishwavidyalaya University Gandhinagar Gujarat 382024 India.
Abdullah AlarifiDepartment of Chemistry, College of Science, King Saud University Riyadh 11451 KSA.
Mohd AfzalDepartment of Chemistry, College of Science, King Saud University Riyadh 11451 KSA.
Naaser A Y AbduhDepartment of Chemistry, College of Science, King Saud University Riyadh 11451 KSA.
Yongtao DuanHenan Provincial Key Laboratory of Children's Genetics and Metabolic Diseases, Zhengzhou Children's Hospital, Zhengzhou University Zhengzhou 450018 China.
Poonam BhadjaArthropod Ecology and Biological Control Research Group, Ton Duc Thang University Ho Chi Minh City Vietnam.ORCID https://orcid.org/0000-0003-2060-4189

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alteration in the pattern of epigenetic marking leads to cancer, neurological disorders, inflammatory problems

Identifiers

PMID35746919
PMCPMC9133982

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.