Evidence map›Paper›PMID 35746635›Full record

ArticleViruses2022

The M13 Phage Assembly Machine Has a Membrane-Spanning Oligomeric Ring Structure.

Maximilian Haase, Lutz Tessmer, Lilian Köhnlechner, Andreas Kuhn

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Maximilian HaaseInstitute of Biology, University of Hohenheim, 70599 Stuttgart, Germany.
Lutz TessmerInstitute of Biology, University of Hohenheim, 70599 Stuttgart, Germany.
Lilian KöhnlechnerInstitute of Biology, University of Hohenheim, 70599 Stuttgart, Germany.
Andreas KuhnInstitute of Biology, University of Hohenheim, 70599 Stuttgart, Germany.ORCID 0000-0003-3738-5744
University of Hohenheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteriophage M13 assembles its progeny particles in the inner membrane of the host. The major component of the assembly machine is G1p and together with G11p it generates an oligomeric structure with a pore-like inner cavity and an ATP hydrolysing domain. This allows the formation of the phage filament, which assembles multiple copies of the membrane-inserted major coat protein G8p around the extruding single-stranded circular DNA. The phage filament then passes through the G4p secretin that is localized in the outer membrane. Presumably, the inner membrane G1p/G11p and the outer G4p form a common complex. To unravel the structural details of the M13 assembly machine, we purified G1p from infected

Indexed as

Bacteriophage M13SecretinCapsid ProteinsEscherichia coliMembrane ProteinsVirus AssemblyCapsid ProteinsMembrane ProteinsSecretinaffinity chromatographybacteriophage M13circular dichroismmembrane proteinphage assembly machine

Identifiers

PMID35746635
PMCPMC9228878
OpenAlexW4281986994

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.