Evidence map›Paper›PMID 35746547›Full record

ArticleVaccines2022

Increasing Uptake of COVID-19 Vaccination and Reducing Health Inequalities in Patients on Renal Replacement Therapy-Experience from a Single Tertiary Centre.

Dimitrios Poulikakos, Rajkumar Chinnadurai, Saira Anwar, Amnah Ahmed, Chukwuma Chukwu, Jayne Moore, Emma Hayes, Julie Gorton, David Lewis, Rosie Donne and 3 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Dimitrios PoulikakosDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Rajkumar ChinnaduraiDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Saira AnwarFaculty of Biology, Medicine, and Health, University of Manchester, Manchester M13 9PL, UK.
Amnah AhmedFaculty of Biology, Medicine, and Health, University of Manchester, Manchester M13 9PL, UK.
Chukwuma ChukwuDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.ORCID 0000-0002-9488-2256
Jayne MooreDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Emma HayesDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Julie GortonDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
David LewisDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Rosie DonneDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Elizabeth LamertonDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Rachel MiddletonDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
Edmond O'RiordanDepartment of Renal Medicine, Northern Care Alliance NHS Foundation Trust, Salford M6 8HD, UK.
University of Manchester · GBNorthern Health and Social Care Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 vaccination has changed the landscape of the COVID-19 pandemic; however, decreased uptake due to vaccine hesitancy has been observed, particularly in patients from minority ethnic backgrounds and socially deprived areas. These patient characteristics are common in patients on Renal Replacement Therapy (RRT), a population at extremely high risk of developing serious illness from COVID-19 and who would thus benefit the most from the vaccination programme. We designed a bespoke COVID-19 vaccination programme for our RRT population with the aim of decreasing health inequalities and increasing vaccination uptake.

methodsKey interventions included addressing vaccine hesitancy by deploying the respective clinical teams as trusted messengers, prompt eligible patient identification and notification, the deployment of resources to optimise vaccine administration in a manner convenient to patients, and the timely collection and analysis of local safety and efficacy data. First, COVID-19 vaccination data in relation to ethnicity and social deprivation in our RRT population, measured by the multiple deprivation index, were analysed and compared to uptake data in the total regional adult clinically extremely vulnerable (CEV) population in Greater Manchester (GM). Univariate logistic regression analysis was used to explore the factors associated with not receiving a vaccine.

resultsOut of 1156 RRT patients included in this analysis, 96.7% received the first dose of the vaccination compared to 93% in the cohort of CEV patients in the GM. Age, gender, ethnicity, and a lower index of multiple deprivation were not identified as significant risk factors for poor first dose vaccine uptake in our cohort. Vaccine uptake in Asian and Black RRT patients was 94.9% and 92.3%, respectively, compared to 93% and 76.2% for the same ethnic groups in the reference CEV GM. Vaccine uptake was 96.1% for RRT patients in the lowest quartile of the multiple deprivation index, compared to 90.5% in the GM reference population.

conclusionBespoke COVID-19 vaccination programmes based on local clinical teams as trusted messengers can improve negative attitudes towards vaccination and reduce health inequalities.

Indexed as

COVID-19 vaccinationethnicityhaemodialysishealth inequalitieskidney transplantperitoneal dialysissocial deprivation

Identifiers

PMID35746547
PMCPMC9231261
OpenAlexW4282597731

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.