Evidence map›Paper›PMID 35746514›Full record

ArticleVaccines2022

Evaluation of the Potency of the Pertussis Vaccine in Experimental Infection Model with

Khedidja Tahar Djebbar, Mounia Allouache, Salim Kezzal, Fouzia Benguerguoura, Chafia TouilBoukoffa, Ines Zidi, Rachida Raache, Hadda-Imene Ouzari

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Khedidja Tahar DjebbarLaboratoire de Contrôle de Qualité des Vaccins et Sérums, Département de Contrôle des Produits Biologiques, Institut Pasteur d'Algérie, Route du Petit Staouel, Dely-Brahim 16047, Algeria.
Mounia AllouacheLaboratoire de Contrôle de Qualité des Vaccins et Sérums, Département de Contrôle des Produits Biologiques, Institut Pasteur d'Algérie, Route du Petit Staouel, Dely-Brahim 16047, Algeria.
Salim KezzalLaboratoire de Contrôle de Qualité des Vaccins et Sérums, Département de Contrôle des Produits Biologiques, Institut Pasteur d'Algérie, Route du Petit Staouel, Dely-Brahim 16047, Algeria.
Fouzia BenguerguouraLaboratoire de Contrôle de Qualité des Vaccins et Sérums, Département de Contrôle des Produits Biologiques, Institut Pasteur d'Algérie, Route du Petit Staouel, Dely-Brahim 16047, Algeria.
Chafia TouilBoukoffaLaboratoire de Biologie Cellulaire et Moléculaire-Equipe Cytokines et NO Synthase, Faculté des Sciences Biologiques, Université des Sciences et de la TechnologieHouariBoumedienne (USTHB), Bab Ezzouar 16111, Algeria.
Ines ZidiLaboratoire des Microorganismes et Biomolécules Actives (LR03ES03), Faculté des Sciences de Tunis (FST), Université Tunis El Manar, Campus Universitaire, Tunis 2092, Tunisia.ORCID 0000-0002-1170-4957
Rachida RaacheLaboratoire de Biologie Cellulaire et Moléculaire-Equipe Cytokines et NO Synthase, Faculté des Sciences Biologiques, Université des Sciences et de la TechnologieHouariBoumedienne (USTHB), Bab Ezzouar 16111, Algeria.
Hadda-Imene OuzariLaboratoire des Microorganismes et Biomolécules Actives (LR03ES03), Faculté des Sciences de Tunis (FST), Université Tunis El Manar, Campus Universitaire, Tunis 2092, Tunisia.
Institut Pasteur d'Algérie · DZTunis University · TNUniversity of Sciences and Technology Houari Boumediene · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Algeria, vaccination against pertussis is carried out using the whole-cell pertussis vaccine combined with the diphtheria and tetanus toxoids (DTwp). The quality control of vaccines locally produced or imported is carried out before the batch release. The aim of our work was to evaluate the potency of pertussis vaccines. In the present study, five consecutive trials of potency were conducted on samples of the same batch of (DTwp) using the mouse protection test (MPT) against experimental infection of

Indexed as

AlgeriaBordetella pertussisKendrick testLD50relative potencywhole-cell pertussis vaccine

Identifiers

PMID35746514
PMCPMC9230502
OpenAlexW4281661535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.