Evidence map›Paper›PMID 35746458›Full record

ArticleVaccines2022

Serious Underlying Medical Conditions and COVID-19 Vaccine Hesitancy: A Large Cross-Sectional Analysis from Australia.

Daphne Day, Lisa Grech, Mike Nguyen, Nathan Bain, Alastair Kwok, Sam Harris, Hieu Chau, Bryan Chan, Richard Blennerhassett, Louise Nott and 14 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

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  15. Drivers and barriers to COVID-19 vaccination in Australians with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 2 countries.

Daphne DayDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0001-8262-2441
Lisa GrechDepartment of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC 3168, Australia.
Mike NguyenDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0003-3044-1707
Nathan BainDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0002-3320-8444
Alastair KwokDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.
Sam HarrisDepartment of Medical Oncology, Bendigo Health, Bendigo, VIC 3550, Australia.
Hieu ChauDepartment of Oncology, Latrobe Regional Hospital, Traralgon, VIC 3844, Australia.
Bryan ChanDepartment of Oncology, Sunshine Coast Hospital and Health Service, Birtinya, QLD 4575, Australia.
Richard BlennerhassettCentral Coast Haematology, North Gosford, NSW 2250, Australia.
Louise NottIcon Cancer Centre Hobart, Hobart, TAS 7000, Australia.
Nada HamadDepartment of Haematology, St Vincent's Hospital Sydney, Darlinghurst, NSW 2010, Australia.
Annette TognelaMacarthur Cancer Therapy Centre, Campbelltown Hospital, Campbelltown, NSW 2560, Australia.
David HoffmanDr David Hoffman, Fairfield, NSW 2165, Australia.
Amelia McCartneyDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0003-0411-0736
Kate WebberDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0003-4350-0884
Jennifer WongDepartment of Medicine, School of Clinical Sciences, Monash University, Clayton, VIC 3168, Australia.
Craig UnderhillBorder Medical Oncology, Albury, NSW 2640, Australia.
Brett SillarsDepartment of Endocrinology, Sunshine Coast Hospital and Health Service, Birtinya, QLD 4575, Australia.
Antony WinkelSchool of Medicine, Griffith University, Birtinya, QLD 4575, Australia.ORCID 0000-0002-6100-4764
Mark SavageDepartment of Endocrinology, Bendigo Health, Bendigo, VIC 3550, Australia.
Bao Sheng LoeThe Psychometrics Centre, University of Cambridge, Cambridge CB2 1AG, UK.
Daniel FreemanDepartment of Psychiatry, University of Oxford, Oxford OX3 7JX, UK.
Eva SegelovDepartment of Oncology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0002-4410-6144
On Behalf Of The Canvaccs Diabvaccs And Msvaccs Investigators
Monash Health · AUBendigo Health · AUGriffith University · AUUNSW Sydney · AUCamden and Campbelltown Hospitals · AUGosford Hospital · AULatrobe Regional Hospital · AUMonash University · AUNational Health Service · GBSunshine Coast University Hospital · AUUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As COVID-19 vaccinations became available and were proven effective in preventing serious infection, uptake amongst individuals varied, including in medically vulnerable populations. This cross-sectional multi-site study examined vaccine uptake, hesitancy, and explanatory factors amongst people with serious and/or chronic health conditions, including the impact of underlying disease on attitudes to vaccination. A 42-item survey was distributed to people with cancer, diabetes, or multiple sclerosis across ten Australian health services from 30 June to 5 October 2021. The survey evaluated sociodemographic and disease-related characteristics and incorporated three validated scales measuring vaccine hesitancy and vaccine-related beliefs generally and specific to their disease: the Oxford COVID-19 Vaccine Hesitancy Scale, the Oxford COVID-19 Vaccine Confidence and Complacency Scale and the Disease Influenced Vaccine Acceptance Scale-Six. Among 4683 participants (2548 [54.4%] female, 2108 [45.0%] male, 27 [0.6%] other; mean [SD] age, 60.6 [13.3] years; 3560 [76.0%] cancer, 842 [18.0%] diabetes, and 281 [6.0%] multiple sclerosis), 3813 (81.5%) self-reported having at least one COVID-19 vaccine. Unvaccinated status was associated with younger age, female sex, lower education and income, English as a second language, and residence in regional areas. Unvaccinated participants were more likely to report greater vaccine hesitancy and more negative perceptions toward vaccines. Disease-related vaccine concerns were associated with unvaccinated status and hesitancy, including greater complacency about COVID-19 infection, and concerns relating to vaccine efficacy and impact on their disease and/or treatment. This highlights the need to develop targeted strategies and education about COVID-19 vaccination to support medically vulnerable populations and health professionals.

Indexed as

cancerCOVID-19diabetesmultiple sclerosisvaccine hesitancy

Identifiers

PMID35746458
PMCPMC9230066
OpenAlexW4281912666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.