Evidence map›Paper›PMID 35746069›Full record

ArticlePolymers2022

Effect of Polyhydroxyalkanoate (PHA) Concentration on Polymeric Scaffolds Based on Blends of Poly-L-Lactic Acid (PLLA) and PHA Prepared via Thermally Induced Phase Separation (TIPS).

Francesco Lopresti, Antonio Liga, Elisa Capuana, Davide Gulfi, Claudio Zanca, Rosalinda Inguanta, Valerio Brucato, Vincenzo La Carrubba, Francesco Carfì Pavia

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Francesco LoprestiDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.
Antonio LigaDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.
Elisa CapuanaDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.
Davide GulfiDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.
Claudio ZancaDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.
Rosalinda InguantaDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.ORCID 0000-0001-8166-7998
Valerio BrucatoDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.ORCID 0000-0001-8309-5735
Vincenzo La CarrubbaDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.
Francesco Carfì PaviaDepartment of Engineering, University of Palermo, RU INSTM, Viale delle Scienze, 90128 Palermo, Italy.ORCID 0000-0001-5107-5588
National Interuniversity Consortium of Materials Science and Technology · ITConsorzio Catania Ricerche · IT

Funding

European Social Fund (ESF) - PON A.I.M: Attraction and International Mobility AIM1845825 - 1
6 · The paper itself

Abstract

Hybrid porous scaffolds composed of both natural and synthetic biopolymers have demonstrated significant improvements in the tissue engineering field. This study investigates for the first time the fabrication route and characterization of poly-L-lactic acid scaffolds blended with polyhydroxyalkanoate up to 30 wt%. The hybrid scaffolds were prepared by a thermally induced phase separation method starting from ternary solutions. The microstructure of the hybrid porous structures was analyzed by scanning electron microscopy and related to the blend composition. The porosity and the wettability of the scaffolds were evaluated through gravimetric and water contact angle measurements, respectively. The scaffolds were also characterized in terms of the surface chemical properties via Fourier transform infrared spectroscopy in attenuated total reflectance. The mechanical properties were analyzed through tensile tests, while the crystallinity of the PLLA/PHA scaffolds was investigated by differential scanning calorimetry and X-ray diffraction.

Indexed as

biopolymer blendsporous structuresscaffoldthermally induced phase separationtissue engineering

Identifiers

PMID35746069
PMCPMC9229920
OpenAlexW4283164932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.