Evidence map›Paper›PMID 35745896›Full record

ArticlePolymers2022

Nanostructured Polyacrylamide Hydrogels with Improved Mechanical Properties and Antimicrobial Behavior.

Elena Olăreț, Ștefan Ioan Voicu, Ruxandra Oprea, Florin Miculescu, Livia Butac, Izabela-Cristina Stancu, Andrada Serafim

Abstract read
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. RUORSC advances · 2024
    Article
  6. Article
  7. A Novel Concept of Nano-Enhanced Phase Change Material.Materials (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elena OlărețAdvanced Polymer Materials Group, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-9593-6140
Ștefan Ioan VoicuAdvanced Polymer Materials Group, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0001-7191-7471
Ruxandra OpreaFaculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 011061 Bucharest, Romania.
Florin MiculescuFaculty of Materials Science and Engineering, University Politehnica of Bucharest, 060042 Bucharest, Romania.ORCID 0000-0001-6757-5616
Livia ButacFaculty of Chemical Engineering and Biotechnologies, University Politehnica of Bucharest, 011061 Bucharest, Romania.
Izabela-Cristina StancuAdvanced Polymer Materials Group, University Politehnica of Bucharest, 011061 Bucharest, Romania.ORCID 0000-0003-0685-3947
Andrada SerafimAdvanced Polymer Materials Group, University Politehnica of Bucharest, 011061 Bucharest, Romania.

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P1-1.1-TE-2019-1161
6 · The paper itself

Abstract

This work proposes a simple method to obtain nanostructured hydrogels with improved mechanical characteristics and relevant antibacterial behavior for applications in articular cartilage regeneration and repair. Low amounts of silver-decorated carbon-nanotubes (Ag@CNTs) were used as reinforcing agents of the semi-interpenetrating polymer network, consisting of linear polyacrylamide (PAAm) embedded in a PAAm-methylene-bis-acrylamide (MBA) hydrogel. The rational design of the materials considered a specific purpose for each employed species: (1) the classical PAAm-MBA network provides the backbone of the materials; (2) the linear PAAm (i) aids the dispersion of the nanospecies, ensuring the systems' homogeneity and (ii) enhances the mechanical properties of the materials with regard to resilience at repeated compressions and ultimate compression stress, as shown by the specific mechanical tests; and (3) the Ag@CNTs (i) reinforce the materials, making them more robust, and (ii) imprint antimicrobial characteristics on the obtained scaffolds. The tests also showed that the obtained materials are stable, exhibiting little degradation after 4 weeks of incubation in phosphate-buffered saline. Furthermore, as revealed by micro-computed tomography, the morphometric features of the scaffolds are adequate for applications in the field of articular tissue regeneration and repair.

Indexed as

antibacterial activitymechanical propertiesnanostructured polyacrylamidesilver-decorated carbon nanotubes

Identifiers

PMID35745896
PMCPMC9227893

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.