Evidence map›Paper›PMID 35745788›Full record

ArticlePharmaceutics2022

Liposomal β-Sitosterol Suppresses Metastasis of CT26/luc Colon Carcinoma via Inhibition of MMP-9 and Evoke of Immune System.

Chao-Yu Shen, Chia-Fen Lee, Wei-Taur Chou, Jeng-Jong Hwang, Yeu-Sheng Tyan, Hui-Yen Chuang

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Journal of pain research · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Phytochemical Study ofMetabolites · 2022
    Article
  10. Review
  11. Research Progress ofIntegrative cancer therapies
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Chao-Yu ShenDepartment of Medical Imaging, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, Taichung City 40201, Taiwan.ORCID 0000-0003-3571-0697
Chia-Fen LeeDepartment of Radiology, Changhua Christian Hospital, Changhua 50006, Taiwan.
Wei-Taur ChouDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.
Jeng-Jong HwangDepartment of Medical Imaging, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, Taichung City 40201, Taiwan.
Yeu-Sheng TyanDepartment of Medical Imaging, Chung Shan Medical University Hospital, School of Medicine, Chung Shan Medical University, Taichung City 40201, Taiwan.
Hui-Yen ChuangDepartment of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Chung Shan Medical University Hospital · TWChanghua Christian Hospital · TWChung Shan Medical University · TWNational Yang Ming Chiao Tung University · TW

Funding

Cheng Hsien General Hospital-National Yang-Ming University Joint Research Program, Taipei, Taiwan CY10718Chung Shan Medical University Hospital, Taichung, Taiwan CSH-2020-C-024Ministry of Science and Technology (MOST) of Taiwan MOST 109-2314-B-010 -006 -MY2
6 · The paper itself

Abstract

β-sitosterol (SITO) has been reported with anticancer effects; however, with poor bioavailability. The current study aimed to investigate whether liposomal encapsulated β-sitosterol (LS) has a better inhibition effect on tumor metastasis than β-sitosterol in a CT26/

Indexed as

bioluminescent imagingCT26/luc colorectal carcinomainterferon-γinterleukin-12interleukin-18liposomal β-sitosterolMMP-9

Identifiers

PMID35745788
PMCPMC9231002
OpenAlexW4282825526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.