Evidence map›Paper›PMID 35745712›Full record

ArticlePharmaceutics2022

Dissolution from Ethylene Vinyl Acetate Copolymer Long-Acting Implants: Effect of Model Active Ingredient Size and Shape.

Anne M Gohn, Amy Nolte, Ethan Ravotti, Seth P Forster, Morgan Giles, Nathan Rudd, Gamini Mendis

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anne M GohnSchool of Engineering, Penn State Behrend, 4701 College Drive, Erie, PA 16563, USA.ORCID 0000-0001-6168-5187
Amy NolteSchool of Engineering, Penn State Behrend, 4701 College Drive, Erie, PA 16563, USA.
Ethan RavottiSchool of Engineering, Penn State Behrend, 4701 College Drive, Erie, PA 16563, USA.
Seth P ForsterMerck & Co., Inc., Rahway, NJ 07033, USA.ORCID 0000-0001-6072-1959
Morgan GilesMerck & Co., Inc., Rahway, NJ 07033, USA.
Nathan RuddMerck & Co., Inc., Rahway, NJ 07033, USA.
Gamini MendisSchool of Engineering, Penn State Behrend, 4701 College Drive, Erie, PA 16563, USA.
Pennsylvania State University · USMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

Pennsylvania Department of Community and Economic Development Manufacturing PA Innovation Program
6 · The paper itself

Abstract

In recent pharmaceutical applications, an active pharmaceutical ingredient (API) can be mixed with a polymer material to yield a composite long-acting drug-delivery device. These devices boast higher patient compliance, localized drug delivery, and lower dosage concentrations, which can increase patient safety. As a laboratory-safe option, calcium carbonate (CaCO

Indexed as

calcium carbonatedissolutiondrug deliverydrug releaseethylene vinyl acetateEVAmigrationpharmaceutical

Identifiers

PMID35745712
PMCPMC9231147
OpenAlexW4281701040

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.