Evidence map›Paper›PMID 35745651›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

The Use of Endo-Cellulase and Endo-Xylanase for the Extraction of Apple Pectins as Factors Modifying Their Anticancer Properties and Affecting Their Synergy with the Active Form of Irinotecan.

Jerzy Maksymowicz, Anna Palko-Łabuz, Beata Sobieszczańska, Mateusz Chmielarz, Mirosława Ferens-Sieczkowska, Magdalena Skonieczna, Agnieszka Wikiera, Olga Wesołowska, Kamila Środa-Pomianek

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jerzy MaksymowiczDepartment of Biophysics and Neuroscience, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Anna Palko-ŁabuzDepartment of Biophysics and Neuroscience, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Beata SobieszczańskaDepartment of Microbiology, Wroclaw Medical University, 50-367 Wrocław, Poland.ORCID 0000-0002-3355-2480
Mateusz ChmielarzDepartment of Biophysics and Neuroscience, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0002-5364-6556
Mirosława Ferens-SieczkowskaDepartment of Chemistry and Immunochemistry, Wroclaw Medical University, 50-367 Wroclaw, Poland.
Magdalena SkoniecznaDepartment of Systems Biology and Engineering, The Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0002-6263-9585
Agnieszka WikieraDepartment of Biotechnology and General Technology of Foods, Faculty of Food Technology, University of Agriculture in Krakow, 31-120 Krakow, Poland.
Olga WesołowskaDepartment of Biophysics and Neuroscience, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0003-1659-3288
Kamila Środa-PomianekDepartment of Biophysics and Neuroscience, Wroclaw Medical University, 50-367 Wroclaw, Poland.ORCID 0000-0003-3454-5044
Wroclaw Medical University · PLSilesian University of Technology · PLUniversity of Agriculture in Krakow · PL

Funding

Ministry of Science and Higher Education RID.Z501.20.013Silesian University of Technology in Gliwice 02/040/SDU/10-21-01
6 · The paper itself

Abstract

Pectin constitutes an essential component of dietary fiber. Modified pectins from various sources possess potent anticancer and immunomodulatory activities. In this study, two pectins isolated from apple pomace by

Indexed as

apoptosiscolon cancerenzymatic extractioninflammationpectinSN-38 (irinotecan)synergy

Identifiers

PMID35745651
PMCPMC9229824
OpenAlexW4282596625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.