Evidence map›Paper›PMID 35745643›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Purification, Characterization and Evaluation of the Antitumoral Activity of a Phospholipase A2 from the Snake

Breno Emanuel Farias Frihling, Ana Paula de Araújo Boleti, Caio Fernando Ramalho de Oliveira, Simone Camargo Sanches, Pedro Henrique de Oliveira Cardoso, Newton Verbisck, Maria Lígia Rodrigues Macedo, Paula Helena Santa Rita, Cristiano Marcelo Espinola Carvalho, Ludovico Migliolo

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Breno Emanuel Farias FrihlingS-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.
Ana Paula de Araújo BoletiS-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.
Caio Fernando Ramalho de OliveiraFaculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande 79603-011, MS, Brazil.ORCID 0000-0001-9549-4848
Simone Camargo SanchesS-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.
Pedro Henrique de Oliveira CardosoS-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.
Newton VerbisckEmbrapa Gado de Corte, Campo Grande 79106-550, MS, Brazil.ORCID 0000-0001-9817-7223
Maria Lígia Rodrigues MacedoFaculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal de Mato Grosso do Sul (UFMS), Campo Grande 79603-011, MS, Brazil.ORCID 0000-0001-6969-6307
Paula Helena Santa RitaBiotério e Serpentário, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.
Cristiano Marcelo Espinola CarvalhoS-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.ORCID 0000-0002-3867-9528
Ludovico MiglioloS-Inova Biotech, Programa de Pós-Graduação em Biotecnologia, Universidade Católica Dom Bosco, Campo Grande 79117-900, MS, Brazil.ORCID 0000-0002-6606-2189
Universidade Católica Dom Bosco · BRUniversidade Federal de Mato Grosso do Sul · BRBrazilian Agricultural Research Corporation · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 01/2018FUNDECT 03/2016National Council for Scientific and Technological Development 04/2021
6 · The paper itself

Abstract

Nature presents a wide range of biomolecules with pharmacological potential, including venomous animal proteins. Among the protein components from snake venoms, phospholipases (PLA

Indexed as

biochemical characterizationcytotoxic activityphospholipase A2

Identifiers

PMID35745643
PMCPMC9230114
OpenAlexW4282545519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.