Evidence map›Paper›PMID 35745638›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Enhanced Thrombin Generation Is Associated with Worse Left Ventricular Scarring after ST-Segment Elevation Myocardial Infarction: A Cohort Study.

Ching-Hui Sia, Sock-Hwee Tan, Siew-Pang Chan, Stephanie Marchesseau, Hui-Wen Sim, Leonardo Carvalho, Ruth Chen, Nor Hanim Mohd Amin, Alan Yean-Yip Fong, Arthur Mark Richards and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Observational
  3. Drug-herb Synergistic Interactions between Clopidogrel and Natural Medicine.Cardiovascular & hematological agents in medicinal chemistry · 2024
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Ching-Hui SiaDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.ORCID 0000-0002-2764-2869
Sock-Hwee TanDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 10, Singapore 119228, Singapore.
Siew-Pang ChanNational University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.
Stephanie MarchesseauSavanamed, Calle Gran Vía, 30, Planta 10, 28013 Madrid, Spain.
Hui-Wen SimDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.
Leonardo CarvalhoDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.
Ruth ChenDepartment of Cardiology, Woodlands Health Campus, Tower E, Level 5, Yishun Community Hospital, 2 Yishun Central 2, Singapore 768024, Singapore.
Nor Hanim Mohd AminClinical Research Centre, Sarawak General Hospital, Jalan Hospital, Kuching 93586, Malaysia.
Alan Yean-Yip FongClinical Research Centre, Sarawak General Hospital, Jalan Hospital, Kuching 93586, Malaysia.ORCID 0000-0002-6675-1312
Arthur Mark RichardsCardiovascular Research Institute, National University of Singapore, Singapore 119228, Singapore.
Christina YipDepartment of Laboratory Medicine, Main Building, Level 3, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074, Singapore.
Mark Y ChanDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.
National University of Singapore · SGNational University Heart Centre Singapore · SGSarawak General Hospital · MYNational University Hospital · SGWoodlands Health Campus · SG

Funding

Bayer Healthcare N/ANational Medical Research Council NMRC/CSA-INV/0001/2016National Medical Research Council NMRC/STaR/0022/2014National University of Singapore Yong Loo Lin School of Medicine's Junior Academic Faculty Scheme N/A
6 · The paper itself

Abstract

Acute myocardial infarction (AMI) is associated with heightened thrombin generation. There are limited data relating to thrombin generation and left ventricular (LV) scarring and LV dilatation in post-MI LV remodeling. We studied 113 patients with ST-segment elevation myocardial infarction (STEMI) who had undergone primary percutaneous coronary intervention (PPCI) (

Indexed as

adverse ventricular remodelingcardiovascular magnetic resonance imagingpercutaneous coronary interventionST-segment elevation myocardial infarctionthrombolysis

Identifiers

PMID35745638
PMCPMC9231218
OpenAlexW4281688836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.