Evidence map›Paper›PMID 35745578›Full record

ArticlePharmaceuticals (Basel, Switzerland)2022

Evaluation of Toxic Properties of New Glycopeptide Flavancin on Rats.

Michael I Treshchalin, Vasilisa A Polozkova, Elena I Moiseenko, Helen M Treshalina, Andrey E Shchekotikhin, Eleonora R Pereverzeva

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Michael I TreshchalinGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.ORCID 0000-0002-5652-8686
Vasilisa A PolozkovaGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.ORCID 0000-0001-8643-6427
Elena I MoiseenkoGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Helen M TreshalinaGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.
Andrey E ShchekotikhinGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.ORCID 0000-0002-6595-0811
Eleonora R PereverzevaGause Institute of New Antibiotics, 11 B. Pirogovskaya Street, 119021 Moscow, Russia.ORCID 0000-0001-7368-9695
Gause Institute of New Antibiotics Russian Academy of Medical Sciences · RUD. Mendeleyev University of Chemical Technology of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glycopeptide antibiotics have side effects that limit their clinical use. In view of this, the development of glycopeptides with improved chemotherapeutic properties remains the main direction in the search for new antibacterial drugs. The objective of this study was to evaluate the toxicological characteristics of new semi-synthetic glycopeptide flavancin. Acute and chronic toxicity of antibiotic was evaluated in Wistar rats. The medium lethal dose (LD

Indexed as

acute toxicitychronic toxicityeremomycinflavancinratssemi-synthetic glycopeptide antibioticsvancomycin

Identifiers

PMID35745578
PMCPMC9228439
OpenAlexW4281480674

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.