Evidence map›Paper›PMID 35745572›Full record

ReviewPharmaceuticals (Basel, Switzerland)2022

Technologies for Solubility, Dissolution and Permeation Enhancement of Natural Compounds.

Meshal Alshamrani, Muhammad Khalid Khan, Barkat Ali Khan, Ahmad Salawi, Yosif Almoshari

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Meshal AlshamraniDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-0396-8653
Muhammad Khalid KhanDrug Delivery and Cosmetics Lab (DDCL), Faculty of Pharmacy, Gomal University, D. I. Khan 29050, Pakistan.ORCID 0000-0001-6079-6571
Barkat Ali KhanDrug Delivery and Cosmetics Lab (DDCL), Faculty of Pharmacy, Gomal University, D. I. Khan 29050, Pakistan.ORCID 0000-0003-4920-1770
Ahmad SalawiDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0001-6342-284X
Yosif AlmoshariDepartment of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-8385-6693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current review is based on the advancements in the field of natural therapeutic agents which could be utilized for a variety of biomedical applications and against various diseases and ailments. In addition, several obstacles have to be circumvented to achieve the desired therapeutic effectiveness, among which limited dissolution and/or solubility and permeability are included. To counteract these issues, several advancements in the field of natural therapeutic substances needed to be addressed. Therefore, in this review, the possible techniques for the dissolution/solubility and permeability improvements have been addressed which could enhance the dissolution and permeability up to several times. In addition, the conventional and modern isolation and purification techniques have been emphasized to achieve the isolation and purification of single or multiple therapeutic constituents with convenience and smarter approaches. Moreover, a brief overview of advanced natural compounds with multiple therapeutic effectiveness have also been anticipated. In brief, enough advancements have been carried out to achieve safe, effective and economic use of natural medicinal agents with improved stability, handling and storage.

Indexed as

dissolutionnatural compoundspermeation enhancementsolubility

Identifiers

PMID35745572
PMCPMC9227247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.