Evidence map›Paper›PMID 35745365›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Buffer Components Incorporate into the Framework of Polyserotonin Nanoparticles and Films during Synthesis.

Keuna Jeon, Justin Andrei Asuncion, Alexander Lucien Corbett, Tiange Yuan, Meera Patel, Nesha May Octavio Andoy, Christian Titus Kreis, Oleksandr Voznyy, Ruby May Arana Sullan

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Keuna JeonDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.ORCID 0000-0001-8705-8835
Justin Andrei AsuncionDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.
Alexander Lucien CorbettDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.ORCID 0000-0003-1968-5612
Tiange YuanDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.ORCID 0000-0002-0329-8901
Meera PatelDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.
Nesha May Octavio AndoyDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.
Christian Titus KreisDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.
Oleksandr VoznyyDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.
Ruby May Arana SullanDepartment of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Toronto, ON M1C 1A4, Canada.ORCID 0000-0002-8927-2605
University of Toronto · CA

Funding

Canada Foundation for Innovation 36544Natural Sciences and Engineering Research Council RGPIN-2017-06522Ontario Ministry of Research, Innovation and Science 36544UTSC Research Competitiveness Fund 2021
6 · The paper itself

Abstract

Polyserotonin nanoparticles (PSeNP) and films are bioinspired nanomaterials that have potential in biomedical applications and surface coatings. As studies on polyserotonin (PSe) nanoparticles and films are still in their infancy, synthetic pathways and material development for this new class of nanomaterial await investigation. Here, we sought to determine how different buffers used during the polymerization of serotonin to form nanoparticles and films impact the physicochemical properties of PSe materials. We show that buffer components are incorporated into the polymer matrix, which is also supported by density functional theory calculations. While we observed no significant differences between the elasticity of nanoparticles synthesized in the different buffers, the nanoscale surface properties of PSe films revealed dissimilarities in surface functional groups influenced by solvent molecules. Overall, the results obtained in this work can be used towards the rational design of PSe nanomaterials with tailored properties and for specific applications.

Indexed as

AFM quantitative imaging (QI)atomic force microscopy (AFM)bioinspired nanomaterialselasticity of polyserotoninnanomechanical properties of polyserotoninpolyserotonin filmspolyserotonin nanoparticles

Identifiers

PMID35745365
PMCPMC9227592
OpenAlexW4282546101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.