Evidence map›Paper›PMID 35745273›Full record

ArticleNutrients2022

Probiotic

Mona Abdelhamid, Chunyu Zhou, Cha-Gyun Jung, Makoto Michikawa

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Nutrients · 2025
    Pooled it
  2. Pooled it
  3. ProbioticNutrients · 2022
    Trial
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Isoquinoline alkaloids inChinese herbal medicines · 2026
    Article
  11. Article
  12. Review
  13. Regulating the crosstalk betweenFrontiers in immunology · 2026
    Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mona AbdelhamidDepartment of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Aichi, Nagoya 467-8601, Japan.ORCID 0000-0002-5444-856X
Chunyu ZhouDepartment of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Aichi, Nagoya 467-8601, Japan.
Cha-Gyun JungDepartment of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Aichi, Nagoya 467-8601, Japan.ORCID 0000-0002-0225-0658
Makoto MichikawaDepartment of Biochemistry, Graduate School of Medical Sciences, Nagoya City University, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Aichi, Nagoya 467-8601, Japan.
Nagoya City University · JP

Funding

AMED JP20de010702AMED JP20dk0207050h001Grant-in-Aid for Challenging Exploratory Research 15K15712Grant-in-Aid for Scientific Research C 20K07762
6 · The paper itself

Abstract

Probiotics improve brain function, including memory and cognition, via the microbiome-gut-brain axis. Oral administration of

Indexed as

Alzheimer DiseaseBifidobacterium breveProbioticsAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalGlycogen Synthase Kinase 3 betaHumansMiceMice, TransgenicPhosphorylationAmyloid beta-PeptidesAmyloid beta-Protein PrecursorGlycogen Synthase Kinase 3 betaAkt/GSK-3βAβ42 productionBifidobacterium breve MCC1274glial activationpresenilin 1synapsestau phosphorylation

Identifiers

PMID35745273
PMCPMC9231139
OpenAlexW4283120631

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.