Evidence map›Paper›PMID 35745255›Full record

ReviewNutrients2022

Impact of Zinc Transport Mechanisms on Embryonic and Brain Development.

Jeremy Willekens, Loren W Runnels

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Redesign of Calmodulin for Genetically Encoded ZnChemical & biomedical imaging · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Role of zinc in health and disease.Clinical and experimental medicine · 2024
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Status of Oxidative Stress during Low-Risk Labour: Preliminary Data.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeremy WillekensDepartment of Pharmacology, Rutgers-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.
Loren W RunnelsDepartment of Pharmacology, Rutgers-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.
Johnson University · US

Funding

Regulation of TRPM7 ChannelsR01HL147350 · NHLBI · RBHS-ROBERT WOOD JOHNSON MEDICAL SCHOOL · PI RUNNELS, LOREN W, YUE, LIXIA · 2019 to 2022
$2.4M
NHLBI NIH HHS R01 HL147350NIH HHS R01HL147350
6 · The paper itself

Abstract

The trace element zinc (Zn) binds to over ten percent of proteins in eukaryotic cells. Zn flexible chemistry allows it to regulate the activity of hundreds of enzymes and influence scores of metabolic processes in cells throughout the body. Deficiency of Zn in humans has a profound effect on development and in adults later in life, particularly in the brain, where Zn deficiency is linked to several neurological disorders. In this review, we will summarize the importance of Zn during development through a description of the outcomes of both genetic and early dietary Zn deficiency, focusing on the pathological consequences on the whole body and brain. The epidemiology and the symptomology of Zn deficiency in humans will be described, including the most studied inherited Zn deficiency disease,

Indexed as

AcrodermatitisCation Transport ProteinsAnimalsBrainFemalePregnancyZincCation Transport ProteinsZincbraindevelopmentfetal programmingTRPM7zinczinc deficiency

Identifiers

PMID35745255
PMCPMC9231024
OpenAlexW4283023064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.